GALNT5 - polypeptide N-acetylgalactosaminyltransferase 5 Gene

Homo sapiens

Also known as GALNACT5; GALNAC-T5

Gene ID: 11227 | Gene type: protein coding

About GALNT5

Cytogenetic location: 2q24.1 Genomic coordinates (GRCh38): 2:157,257,705-157,318,491 (from NCBI)

This gene has 3 transcripts (splice variants), 231 orthologues and 19 paralogues. Biased expression in colon (RPKM 10.1), lung (RPKM 7.0) and 7 other tissues.

Summary

The protein encoded by this gene is a membrane-bound polypeptide N-acetylgalactosaminyltransferase that is found in the Golgi. The encoded protein catalyzes the first step in the mucin-type O-glycosylation of Golgi proteins, transfering an N-acetyl-D-galactosamine residue to a serine or threonine residue on the protein receptor. [provided by RefSeq, Aug 2016]

GALNT5 Products(2)

mRNA	Protein	Name
NM_001329868.2	NP_001316797.1	polypeptide N-acetylgalactosaminyltransferase 5 isoform 2
NM_014568.3	NP_055383.1	polypeptide N-acetylgalactosaminyltransferase 5 isoform 1

GALNT5 Protein Structure

Glycos_transf_2

Ricin_B_lectin

0
200
400
600
800
940 a.a.

Protein Preferred Names

Protein Names

polypeptide N-acetylgalactosaminyltransferase 5

UDP-GalNAc:polypeptide N-acetylgalactosaminyltransferase 5

Related Diseases

Diseases

Alias

Atrial Septal Defect 5

ASD5	Atrial Heart Septal Defect 5
Septal Defect, Atrial, Type 5

Diseases	Alias
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS05258	GALNT5 Human Pre-designed siRNA Set A		/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Mus musculus	GALNT5	MGD	MGI:2179403
Bos taurus	GALNT5	VGNC	VGNC:29233
Rattus norvegicus	GALNT5	RGD	RGD:620361
Canis familiaris	GALNT5	VGNC	VGNC:53096
Felis catus	GALNT5	VGNC	VGNC:62452
Macaca mulatta	GALNT5	VGNC	VGNC:72874

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