2. Gene
  3. Egln2 - egl-9 family hypoxia-inducible factor 2 Gene

Egln2 - egl-9 family hypoxia-inducible factor 2 Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Mus musculus

Also known as Ier4; Phd1; SM-20; Hif-p4h-1; 0610011A13Rik

Gene ID: 112406 | Gene type: protein coding

About Egln2

Summary

Predicted to enable ferrous iron binding activity; oxygen sensor activity; and peptidyl-proline 4-dioxygenase activity. Predicted to be involved in several processes, including cell redox homeostasis; cellular response to hypoxia; and peptidyl-proline hydroxylation to 4-hydroxy-L-proline. Predicted to be located in nucleoplasm. Predicted to be active in cytoplasm and nucleus. Is expressed in brain; cerebral cortex; hippocampus; and olfactory epithelium. Human ortholog(s) of this gene implicated in renal cell carcinoma. Orthologous to human EGLN2 (egl-9 family hypoxia inducible factor 2). [provided by Alliance of Genome Resources, Apr 2022]

Egln2 Products(2)

mRNA Protein Name
NM_001357767.1 NP_001344696.1 prolyl hydroxylase EGLN2 isoform 2
NM_053208.4 NP_444438.2 prolyl hydroxylase EGLN2 isoform 1
Protein Preferred Names Protein Names

prolyl hydroxylase EGLN2

HIF-PH1

HIF-prolyl hydroxylase 1

HPH-1

falkor

hypoxia-inducible factor prolyl hydroxylase 1

immediate early response 4

prolyl hydroxylase domain-containing protein 1

Related Agents

Pre-clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS04213 EGLN2 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Egln2 NCBI NCBI:112398