Egln2 - egl-9 family hypoxia-inducible factor 2 Gene
Also Known as Ier4; Phd1; SM-20; Hif-p4h-1; 0610011A13Rik
Species: Mus musculus
Summary
Predicted to enable ferrous iron binding activity; oxygen sensor activity; and peptidyl-proline 4-dioxygenase activity. Predicted to be involved in several processes, including cell redox homeostasis; cellular response to hypoxia; and peptidyl-proline hydroxylation to 4-hydroxy-L-proline. Predicted to be located in nucleoplasm. Predicted to be active in cytoplasm and nucleus. Is expressed in brain; cerebral cortex; hippocampus; and olfactory epithelium. Human ortholog(s) of this gene implicated in renal cell carcinoma. Orthologous to human EGLN2 (egl-9 family hypoxia inducible factor 2). [provided by Alliance of Genome Resources, Apr 2022]
Egln2 Products (2)
| mRNA | Protein | Name |
|---|---|---|
| NM_001357767.1 | NP_001344696.1 | prolyl hydroxylase EGLN2 isoform 2 |
| NM_053208.4 | NP_444438.2 | prolyl hydroxylase EGLN2 isoform 1 |
| Protein Preferred Names | Protein Names | |
|---|---|---|
|
prolyl hydroxylase EGLN2 |
|
|
Related Agents
- Pre-clinical Phase
Pre-clinical Phase
| Cat. No. | Product Name |
Effect
|
Purity |
Rare Diseases
|
|---|---|---|---|---|
| HY-RS04213 | EGLN2 Human Pre-designed siRNA Set A | Pre-designed Set | / | Unkown |
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