FILIP1L - filamin A interacting protein 1 like Gene

Also Known as DOC1; DOC-1; GIP90; GIP130

Species: Homo sapiens

Gene Type: protein coding
Gene ID: 11259

About FILIP1L

Cytogenetic location: 3q12.1 Genomic coordinates (GRCh38): 3:99,828,811-100,114,501 (from NCBI)

This gene has 10 transcripts (splice variants), 265 orthologues and 3 paralogues. Ubiquitous expression in gall bladder (RPKM 44.5), urinary bladder (RPKM 29.8) and 23 other tissues.

Summary

Predicted to be located in cytoplasm; membrane; and nucleus. [provided by Alliance of Genome Resources, Apr 2022]

FILIP1L Products (9)

mRNA Protein Name
NM_001042459.3 NP_001035924.1 filamin A-interacting protein 1-like isoform 3
NM_001282793.2 NP_001269722.1 filamin A-interacting protein 1-like isoform 4
NM_001282794.2 NP_001269723.1 filamin A-interacting protein 1-like isoform 5
NM_001370247.1 NP_001357176.1 filamin A-interacting protein 1-like isoform 2
NM_001387850.1 NP_001374779.1 filamin A-interacting protein 1-like isoform 6
NM_001387851.1 NP_001374780.1 filamin A-interacting protein 1-like isoform 7
NM_001387852.1 NP_001374781.1 filamin A-interacting protein 1-like isoform 8
NM_014890.4 NP_055705.2 filamin A-interacting protein 1-like isoform 2
NM_182909.4 NP_878913.2 filamin A-interacting protein 1-like isoform 1

Gene Ontology

  • Molecular Function
Molecular Function GO Annotation Evidence References Source
enables protein binding IPI
IPI: Inferred from physical interaction
32296183 GOA
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

FILIP1L Protein Structure

CortBP2

CortBP2: Cortactin-binding protein-2 (58 - 248)

  • 0
  • 200
  • 400
  • 600
  • 800
  • 1000
  • 1135 a.a.
Protein Preferred Names Protein Names

filamin A-interacting protein 1-like

  • 130 kDa GPBP-interacting protein

Related Diseases

Diseases Alias
Ovarian Cancer 1

  • Ovarian Cancer, Susceptibility To

  • Ovarian Cancer, Susceptibility To, 1

  • OVCAS1

  • Ovarian Cancer

  • Ovarian Carcinoma

  • Malignant Neoplasm Of Ovary

  • Epithelial Ovarian Cancer
Ovarian Cancer

  • Ovarian Carcinoma

  • Ovarian Neoplasm

  • Malignant Tumour Of Ovary

  • Cancer Of The Ovary

  • Epithelial Ovarian Cancer

  • Neoplasm Of Ovary

  • Ovarian Neoplasms

  • Ovarian Cancers

  • Malignant Neoplasm Of Ovary

  • Primary Malignant Neoplasm Of Ovary

  • Ovarian Cancer, Somatic

  • Malignant Ovarian Tumor

  • Ovary Neoplasm

  • Primary Ovarian Cancer

  • Tumor Of The Ovary

  • Malignant Neoplasm Of The Ovary

  • Malignant Tumor Of The Ovary

  • Ovarian Malignant Tumor

  • OC

  • Ovarian Carcinomas

  • Cancer, Ovarian

  • Cancer Of Ovary

  • Ovary Cancer

  • Ca Ovary
Macular Degeneration, Age-Related, 1

  • Macular Degeneration

  • Age-Related Macular Degeneration

  • Macular Degeneration, Age-Related

  • Age Related Macular Degeneration

  • Age Related Macular Degeneration 1

  • ARMD1

  • Senile Macular Degeneration

  • Maculopathy, Age-Related, 1

  • Macular Degeneration, Age-Related, Reduced Risk Of

  • Age Related Maculopathy 1

  • Age Related Maculopathies

  • Age Related Maculopathy

  • Senile Macular Retinal Degeneration

  • Macular Degeneration Of Retina

  • Age-Related Maculopathy

  • Amd

  • Armd

  • Age-Related Maculopathy, Susceptibility To

  • Maculopathy Age-Related

  • Macular Degeneration, Age-Related, 1, Susceptibility To

  • Maculopathy, Age-Related

  • Macular Degeneration, Age-Related, Type 1

  • Macular Degeneration, Age-Related, 2
Cerebrooculofacioskeletal Syndrome 1

  • Cofs Syndrome

  • COFS1

  • Pena-Shokeir Syndrome Type 2

  • Cofs

  • Pena-Shokeir Syndrome, Type Ii

  • Cerebrooculofacioskeletal Syndrome

  • Cerebro-Oculo-Facio-Skeletal Syndrome 1

  • Pena Shokeir Syndrome Type 2
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS04949 FILIP1L Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Bos taurus FILIP1L VGNC VGNC:29013
Mus musculus FILIP1L MGD MGI:1925999
Rattus norvegicus FILIP1L RGD RGD:1565927
Canis familiaris FILIP1L VGNC VGNC:40882
Macaca mulatta FILIP1L VGNC VGNC:72562
Felis catus FILIP1L VGNC VGNC:62274
Others FILIP1L NCBI