Slc6a20a - solute carrier family 6 member 20a Gene

Also Known as Xtrp3; rB21a; Slc6a20

Species: Rattus norvegicus

Gene Type: protein coding
Gene ID: 113918

Summary

Enables L-proline transmembrane transporter activity; amino-acid betaine transmembrane transporter activity; and proline:sodium symporter activity. Involved in L-proline import across plasma membrane and amino-acid betaine transport. Predicted to be located in apical plasma membrane. Predicted to be integral component of plasma membrane. Human ortholog(s) of this gene implicated in iminoglycinuria. Orthologous to human SLC6A20 (solute carrier family 6 member 20). [provided by Alliance of Genome Resources, Apr 2022]

Slc6a20a Products (1)

mRNA Protein Name
NM_133296.2 NP_579830.2 sodium- and chloride-dependent transporter XTRP3

Gene Ontology

  • Molecular Function
  • Biological Process
Molecular Function GO Annotation Evidence References Source
enables L-proline transmembrane transporter activity IDA
IDA: Inferred from direct assay
15632147 RGD
enables amino acid transmembrane transporter activity IDA
IDA: Inferred from direct assay
15632147 RGD
enables amino-acid betaine transmembrane transporter activity IMP
IMP: Inferred from mutant phenotype
26028423 RGD
enables proline:sodium symporter activity IDA
IDA: Inferred from direct assay
15632147 RGD
Biological Process GO Annotation Evidence References Source
involved in L-proline import across plasma membrane IDA
IDA: Inferred from direct assay
15632147 RGD
involved in amino acid import across plasma membrane IDA
IDA: Inferred from direct assay
15632147 RGD
involved in amino acid transport IDA
IDA: Inferred from direct assay
15632147 RGD
involved in amino-acid betaine transport IMP
IMP: Inferred from mutant phenotype
26028423 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

sodium- and chloride-dependent transporter XTRP3

  • X transporter protein 3

  • sodium/imino-acid transporter 1

  • solute carrier family 6 (neurotransmitter transporter), member 20

  • solute carrier family 6 (proline IMINO transporter), member 20

  • solute carrier family 6 member 20

  • transporter rB21A

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS13307 SLC6A20 Human Pre-designed siRNA Set A Pre-designed Set / Unkown