ADCY8 - adenylate cyclase 8 Gene
Also Known as AC8; ADCY3; HBAC1
Species: Homo sapiens
About ADCY8
This gene has 3 transcripts (splice variants), 197 orthologues and 17 paralogues. Biased expression in brain (RPKM 4.1), lung (RPKM 0.8) and 2 other tissues.
Summary
Adenylate Cyclase is a membrane bound enzyme that catalyses the formation of cyclic AMP from ATP. The enzymatic activity is under the control of several Hormones, and different polypeptides participate in the transduction of the signal from the receptor to the catalytic moiety. Stimulatory or inhibitory receptors (Rs and Ri) interact with G proteins (Gs and Gi) that exhibit GTPase activity and they modulate the activity of the catalytic subunit of the adenylyl cyclase [provided by RefSeq, Jul 2008]
ADCY8 Products (1)
| mRNA | Protein | Name |
|---|---|---|
| NM_001115.3 | NP_001106.1 | adenylate cyclase type 8 |
ADCY8 Protein Structure
Guanylate_cyc: Adenylate and Guanylate cyclase catalytic domain (406 - 588)
DUF1053: Domain of Unknown Function (DUF1053) (618 - 712)
Guanylate_cyc: Adenylate and Guanylate cyclase catalytic domain (974 - 1171)
- 0
- 200
- 400
- 600
- 800
- 1000
- 1251 a.a.
| Protein Preferred Names | Protein Names | |
|---|---|---|
|
adenylate cyclase type 8 |
|
Related Diseases
| Diseases | Alias | |
|---|---|---|
| Dissociative Amnesia |
|
|
| Joubert Syndrome 24 |
|
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| Nemaline Myopathy 7 |
|
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| Dissociative Disorder |
|
|
Related Agents
- Pre-clinical Phase
Pre-clinical Phase
| Cat. No. | Product Name |
Effect
|
Purity |
Rare Diseases
|
|---|---|---|---|---|
| HY-RS00334 | ADCY8 Human Pre-designed siRNA Set A | Pre-designed Set | / | Unkown |
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