Glrx2 - glutaredoxin 2 Gene

Species: Rattus norvegicus

Gene Type: protein coding
Gene ID: 114022

Summary

Predicted to enable protein-disulfide reductase activity. Involved in aging and cellular response to superoxide. Located in several cellular components, including dendrite; mitochondrial matrix; and neuronal cell body. Orthologous to human GLRX2 (glutaredoxin 2). [provided by Alliance of Genome Resources, Apr 2022]

Glrx2 Products (3)

mRNA Protein Name
NM_001394170.1 NP_001381099.1 glutaredoxin-2, mitochondrial 1
NM_001394171.1 NP_001381100.1 glutaredoxin-2, mitochondrial 2
NM_001394172.1 NP_001381101.1 glutaredoxin-2, mitochondrial 2

Gene Ontology

  • Biological Process
  • Cellular Component
Biological Process GO Annotation Evidence References Source
involved in cellular response to superoxide IEP
IEP: Inferred from expression pattern
25126518 RGD
Cellular Component GO Annotation Evidence References Source
located in dendrite IDA
IDA: Inferred from direct assay
20620191 RGD
located in mitochondrial matrix IDA
IDA: Inferred from direct assay
17845131 RGD
located in neuronal cell body IDA
IDA: Inferred from direct assay
20620191 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

glutaredoxin-2, mitochondrial

  • glutaredoxin 2 (thioltransferase)

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS05497 GLRX2 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Glrx2 NCBI NCBI:51022