Ctnnd2 - catenin delta 2 Gene

Species: Rattus norvegicus

Gene Type: protein coding
Gene ID: 114028

Summary

Predicted to enable beta-catenin binding activity and Cadherin binding activity. Predicted to be involved in several processes, including cell-cell junction assembly; dendritic spine morphogenesis; and regulation of canonical Wnt signaling pathway. Predicted to act upstream of or within learning; morphogenesis of a branching structure; and regulation of synaptic plasticity. Located in neuron projection and nucleus. Is active in postsynaptic density. Human ortholog(s) of this gene implicated in anxiety disorder; major depressive disorder; and schizophrenia. Orthologous to human CTNND2 (catenin delta 2). [provided by Alliance of Genome Resources, Apr 2022]

Ctnnd2 Products (1)

mRNA Protein Name
NM_001271502.1 NP_001258431.1 catenin delta-2

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables protein binding IPI
IPI: Inferred from physical interaction
10896674 RGD
enables structural constituent of postsynaptic density IDA
IDA: Inferred from direct assay
17687028 RGD
enables structural constituent of postsynaptic density IMP
IMP: Inferred from mutant phenotype
17687028 RGD
Biological Process GO Annotation Evidence References Source
involved in regulation of postsynaptic membrane neurotransmitter receptor levels IDA
IDA: Inferred from direct assay
17687028 RGD
involved in regulation of postsynaptic membrane neurotransmitter receptor levels IEP
IEP: Inferred from expression pattern
17687028 RGD
involved in regulation of postsynaptic membrane neurotransmitter receptor levels IMP
IMP: Inferred from mutant phenotype
17687028 RGD
Cellular Component GO Annotation Evidence References Source
is active in glutamatergic synapse IDA
IDA: Inferred from direct assay
17687028 RGD
is active in glutamatergic synapse IMP
IMP: Inferred from mutant phenotype
17687028 RGD
is active in postsynaptic density IDA
IDA: Inferred from direct assay
12453475 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

catenin delta-2

  • catenin (cadherin-associated protein), delta 2 (neural plakophilin-related arm-repeat protein)

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS03312 CTNND2 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Ctnnd2 NCBI NCBI:1501