1. Gene
  2. Sc5d - sterol-C5-desaturase Gene

Sc5d - sterol-C5-desaturase Gene

Rattus norvegicus

Also known as Sc5dl

Gene ID: 114100 | Gene type: protein coding

About Sc5d

Summary

Enables C-5 sterol desaturase activity. Involved in Cholesterol biosynthetic process via lathosterol. Located in intracellular membrane-bounded organelle. Orthologous to human SC5D (sterol-C5-desaturase). [provided by Alliance of Genome Resources, Apr 2022]

Sc5d Products(1)

mRNA Protein Name
NM_053642.2 NP_446094.1 lathosterol oxidase
Gene Ontology
  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence Reference Source
enables C-5 sterol desaturase activity IDA
IDA: Inferred from direct assay
7961720 RGD
enables delta7-sterol 5(6)-desaturase activity IDA
IDA: Inferred from direct assay
4019441 RGD
Biological Process GO Annotation Evidence Reference Source
involved in cholesterol biosynthetic process via lathosterol IDA
IDA: Inferred from direct assay
4019441 RGD
Cellular Component GO Annotation Evidence Reference Source
is active in endoplasmic reticulum membrane IDA
IDA: Inferred from direct assay
4019441 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

lathosterol oxidase

C-5 sterol desaturase

delta(7)-sterol 5-desaturase

delta(7)-sterol C5(6)-desaturase

lathosterol 5-desaturase

sterol-C5-desaturase (ERG3 delta-5-desaturase homolog, S. cerevisiae)-like

sterol-C5-desaturase (fungal ERG3, delta-5-desaturase) homolog

st

Orthologs Information

Species Symbol Source ID
Homo sapiens Sc5d NCBI NCBI:6309