Sc5d - sterol-C5-desaturase Gene

Also Known as Sc5dl

Species: Rattus norvegicus

Gene Type: protein coding
Gene ID: 114100

Summary

Enables C-5 sterol desaturase activity. Involved in Cholesterol biosynthetic process via lathosterol. Located in intracellular membrane-bounded organelle. Orthologous to human SC5D (sterol-C5-desaturase). [provided by Alliance of Genome Resources, Apr 2022]

Sc5d Products (1)

mRNA Protein Name
NM_053642.2 NP_446094.1 lathosterol oxidase

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables C-5 sterol desaturase activity IDA
IDA: Inferred from direct assay
7961720 RGD
enables delta7-sterol 5(6)-desaturase activity IDA
IDA: Inferred from direct assay
4019441 RGD
Biological Process GO Annotation Evidence References Source
involved in cholesterol biosynthetic process via lathosterol IDA
IDA: Inferred from direct assay
4019441 RGD
Cellular Component GO Annotation Evidence References Source
is active in endoplasmic reticulum membrane IDA
IDA: Inferred from direct assay
4019441 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

lathosterol oxidase

  • C-5 sterol desaturase

  • delta(7)-sterol 5-desaturase

  • delta(7)-sterol C5(6)-desaturase

  • lathosterol 5-desaturase

  • sterol-C5-desaturase (ERG3 delta-5-desaturase homolog, S. cerevisiae)-like

  • sterol-C5-desaturase (fungal ERG3, delta-5-desaturase) homolog

  • st

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS12473 SC5D Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Sc5d NCBI NCBI:6309