Actg1 - actin, gamma, cytoplasmic 1 Gene
Also Known as E51; Actg; Actl
Species: Mus musculus
Summary
Actins are highly conserved proteins that are involved in various types of cell motility and maintenance of the Cytoskeleton. In vertebrates, three main groups of actin isoforms, alpha, beta, and gamma, have been identified. The alpha actins are found in muscle tissues and are a major constituent of the contractile apparatus. The beta and gamma actins co-exist in most cell types as components of the Cytoskeleton, and as mediators of internal cell motility. Actin, gamma 1, encoded by this gene, is a cytoplasmic actin found in non-muscle cells. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Sep 2015]
Actg1 Products (2)
| mRNA | Protein | Name |
|---|---|---|
| NM_001313923.1 | NP_001300852.1 | actin, cytoplasmic 2 isoform 2 |
| NM_009609.3 | NP_033739.1 | actin, cytoplasmic 2 isoform 1 |
| Molecular Function GO Annotation | Evidence | References | Source |
|---|---|---|---|
| enables protein binding |
IPI
IPI: Inferred from physical interaction
|
19423573 | MGI |
| enables structural constituent of cytoskeleton |
IDA
IDA: Inferred from direct assay
|
15194427 | MGI |
| Biological Process GO Annotation | Evidence | References | Source |
|---|---|---|---|
| acts upstream of or within cellular response to type II interferon |
IDA
IDA: Inferred from direct assay
|
19144319 | MGI |
| involved in regulation of synaptic vesicle endocytosis |
IDA
IDA: Inferred from direct assay
|
27840001 | MGI |
| involved in regulation of synaptic vesicle endocytosis |
IMP
IMP: Inferred from mutant phenotype
|
27840001 | MGI |
| acts upstream of or within sarcomere organization |
IDA
IDA: Inferred from direct assay
|
15194427 | MGI |
| Cellular Component GO Annotation | Evidence | References | Source |
|---|---|---|---|
| is active in Schaffer collateral - CA1 synapse |
IDA
IDA: Inferred from direct assay
|
27840001 | MGI |
| is active in Schaffer collateral - CA1 synapse |
IMP
IMP: Inferred from mutant phenotype
|
27840001 | MGI |
| located in actin cytoskeleton |
IDA
IDA: Inferred from direct assay
|
15194427 | MGI |
| located in apical part of cell |
IDA
IDA: Inferred from direct assay
|
29891944 | MGI |
| located in basal body patch |
IDA
IDA: Inferred from direct assay
|
29891944 | MGI |
| is active in calyx of Held |
IDA
IDA: Inferred from direct assay
|
27840001 | MGI |
| is active in calyx of Held |
IMP
IMP: Inferred from mutant phenotype
|
27840001 | MGI |
| part of filamentous actin |
IDA
IDA: Inferred from direct assay
|
18796539 | MGI |
| located in myofibril |
IDA
IDA: Inferred from direct assay
|
15194427 | MGI |
| located in phagocytic vesicle |
IDA
IDA: Inferred from direct assay
|
19144319 | MGI |
| Protein Preferred Names | Protein Names | |
|---|---|---|
|
actin, cytoplasmic 2 |
|