2. Gene
  3. CSMD3 - CUB and Sushi multiple domains 3 Gene

CSMD3 - CUB and Sushi multiple domains 3 Gene

  • Gene
  • Protein
  • Disease
  • Agent
  • Ortholog
Homo sapiens
Gene ID: 114788 | Gene type: protein coding

About CSMD3

Cytogenetic location: 8q23.3 Genomic coordinates (GRCh38): 8:112,222,928-113,436,939 (from NCBI)

This gene has 10 transcripts (splice variants), 230 orthologues, 39 paralogues and is associated with 151 phenotypes. Biased expression in brain (RPKM 1.9), testis (RPKM 0.7) and 1 other tissue.

Summary

Predicted to be involved in regulation of dendrite development. Predicted to be located in plasma membrane. [provided by Alliance of Genome Resources, Apr 2022]

CSMD3 Products(4)

mRNA Protein Name
NM_001363185.1 NP_001350114.1 CUB and sushi domain-containing protein 3 isoform 4
NM_052900.3 NP_443132.3 CUB and sushi domain-containing protein 3 isoform 3
NM_198123.2 NP_937756.1 CUB and sushi domain-containing protein 3 isoform 1
NM_198124.2 NP_937757.1 CUB and sushi domain-containing protein 3 isoform 2

CSMD3 Protein Structure

CUB

CUB: CUB domain (65 - 170)

Sushi

Sushi: Sushi repeat (SCR repeat) (178 - 235)

CUB

CUB: CUB domain (241 - 342)

Sushi

Sushi: Sushi repeat (SCR repeat) (486 - 543)

CUB

CUB: CUB domain (548 - 656)

Sushi

Sushi: Sushi repeat (SCR repeat) (664 - 717)

CUB

CUB: CUB domain (721 - 826)

Sushi

Sushi: Sushi repeat (SCR repeat) (834 - 891)

CUB

CUB: CUB domain (895 - 1000)

Sushi

Sushi: Sushi repeat (SCR repeat) (1010 - 1063)

CUB

CUB: CUB domain (1067 - 1174)

Sushi

Sushi: Sushi repeat (SCR repeat) (1182 - 1237)

CUB

CUB: CUB domain (1241 - 1346)

Sushi

Sushi: Sushi repeat (SCR repeat) (1354 - 1410)

CUB

CUB: CUB domain (1414 - 1520)

Sushi

Sushi: Sushi repeat (SCR repeat) (1528 - 1584)

CUB

CUB: CUB domain (1588 - 1693)

Sushi

Sushi: Sushi repeat (SCR repeat) (1701 - 1758)

CUB

CUB: CUB domain (1762 - 1867)

Sushi

Sushi: Sushi repeat (SCR repeat) (1884 - 1935)

CUB

CUB: CUB domain (1939 - 2044)

Sushi

Sushi: Sushi repeat (SCR repeat) (2052 - 2107)

CUB

CUB: CUB domain (2111 - 2216)

Sushi

Sushi: Sushi repeat (SCR repeat) (2224 - 2279)

CUB

CUB: CUB domain (2283 - 2379)

Sushi

Sushi: Sushi repeat (SCR repeat) (2395 - 2452)

CUB

CUB: CUB domain (2464 - 2564)

Sushi

Sushi: Sushi repeat (SCR repeat) (2569 - 2627)

Sushi

Sushi: Sushi repeat (SCR repeat) (2632 - 2689)

Sushi

Sushi: Sushi repeat (SCR repeat) (2694 - 2748)

Sushi

Sushi: Sushi repeat (SCR repeat) (2759 - 2812)

Sushi

Sushi: Sushi repeat (SCR repeat) (2817 - 2870)

Sushi

Sushi: Sushi repeat (SCR repeat) (2875 - 2928)

Sushi

Sushi: Sushi repeat (SCR repeat) (2933 - 2990)

Sushi

Sushi: Sushi repeat (SCR repeat) (2995 - 3048)

Sushi

Sushi: Sushi repeat (SCR repeat) (3056 - 3109)

Sushi

Sushi: Sushi repeat (SCR repeat) (3114 - 3168)

Sushi

Sushi: Sushi repeat (SCR repeat) (3173 - 3228)

Sushi

Sushi: Sushi repeat (SCR repeat) (3233 - 3286)

Sushi

Sushi: Sushi repeat (SCR repeat) (3291 - 3344)

Sushi

Sushi: Sushi repeat (SCR repeat) (3352 - 3406)

Sushi

Sushi: Sushi repeat (SCR repeat) (3411 - 3466)

  • 0
  • 600
  • 1200
  • 1800
  • 2400
  • 3000
  • 3707 a.a.
Protein Preferred Names Protein Names

CUB and sushi domain-containing protein 3

CUB and sushi multiple domains protein 3

Recombinant CSMD3 Proteins

Cat. No. Product Name Accession Purity
HY-P79412 CSMD3 Protein, Human (CHO, His) Q7Z407-1 (A2218-S3306) ≥95%

Related Diseases

Diseases Alias
Uterine Corpus Endometrial Carcinoma
Familial Adult Myoclonic Epilepsy

Benign Adult Familial Myoclonus Epilepsy

Bafme

Benign Adult Familial Myoclonic Epilepsy

Fame

Familial Cortical Myoclonic Tremor And Epilepsy

Fcmte

Adcme

Autosomal Dominant Cortical Myoclonus And Epilepsy

Fam

Epilepsy, Myoclonic, Familial Adult

Epilepsy, Myoclonic, Benign Adult Familial, Type 2
Trichorhinophalangeal Syndrome, Type Ii

Langer-Giedion Syndrome

Lgs

Trichorhinophalangeal Syndrome Type Ii

Trichorhinophalangeal Syndrome Type 2

TRPS2

Monosomy 8q24.1

Chromosome 8q24.1 Deletion Syndrome

Deletion 8q24.1

Giedion-Langer Syndrome

Trichorhinophalangeal Dysplasia Type Ii

Langer Giedion Syndrome

Trps 2

Tricho-Rhino-Phalangeal Syndrome Type Ii

Trichorhinophalangeal Syndrome With Exostosis

Trps Ii

Tricho-Rhino-Phalangeal Syndrome 2

8q24.1 Microdeletion Syndrome

8q24.1 Deletion Syndrome
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS03241 CSMD3 Human Pre-designed siRNA Set A / Unkown

Orthologs Information

Species Symbol Source ID
Felis catus CSMD3 VGNC VGNC:61224
Macaca mulatta CSMD3 VGNC VGNC:71442
Mus musculus CSMD3 MGD MGI:2386403
Canis familiaris CSMD3 VGNC VGNC:39663
Rattus norvegicus CSMD3 RGD RGD:1594530