Cacna1h - calcium voltage-gated channel subunit alpha1 H Gene

Species: Rattus norvegicus

Gene Type: protein coding
Gene ID: 114862

Summary

Enables low voltage-gated Calcium Channel activity. Involved in several processes, including calcium ion import; positive regulation of cardiac muscle cell contraction; and primary alcohol biosynthetic process. Located in several cellular components, including dendrite; nucleus; and perikaryon. Biomarker of sciatic neuropathy. Human ortholog(s) of this gene implicated in childhood absence epilepsy and primary hyperaldosteronism. Orthologous to human CACNA1H (calcium voltage-gated channel subunit alpha1 H). [provided by Alliance of Genome Resources, Apr 2022]

Cacna1h Products (1)

mRNA Protein Name
NM_153814.2 NP_722521.1 voltage-dependent T-type calcium channel subunit alpha-1H

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables low voltage-gated calcium channel activity IDA
IDA: Inferred from direct assay
11073957 RGD
Biological Process GO Annotation Evidence References Source
involved in aldosterone biosynthetic process IMP
IMP: Inferred from mutant phenotype
19342457 RGD
involved in calcium ion import IDA
IDA: Inferred from direct assay
16935432 RGD
involved in calcium ion import IMP
IMP: Inferred from mutant phenotype
19443576 RGD
involved in calcium ion transport IDA
IDA: Inferred from direct assay
11073957 RGD
involved in cortisol biosynthetic process IMP
IMP: Inferred from mutant phenotype
19342457 RGD
involved in positive regulation of cardiac muscle cell contraction IMP
IMP: Inferred from mutant phenotype
19443576 RGD
Cellular Component GO Annotation Evidence References Source
located in dendrite IDA
IDA: Inferred from direct assay
16736476 RGD
located in perikaryon IDA
IDA: Inferred from direct assay
16736476 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

voltage-dependent T-type calcium channel subunit alpha-1H

  • calcium channel, voltage-dependent, T type, alpha 1H subunit

  • voltage-gated calcium channel subunit alpha Cav3.2

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS01798 CACNA1H Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Cacna1h NCBI NCBI:8912