Cacna1h - calcium voltage-gated channel subunit alpha1 H Gene

Rattus norvegicus

Gene ID: 114862 | Gene type: protein coding

About Cacna1h

Summary

Enables low voltage-gated Calcium Channel activity. Involved in several processes, including calcium ion import; positive regulation of cardiac muscle cell contraction; and primary alcohol biosynthetic process. Located in several cellular components, including dendrite; nucleus; and perikaryon. Biomarker of sciatic neuropathy. Human ortholog(s) of this gene implicated in childhood absence epilepsy and primary hyperaldosteronism. Orthologous to human CACNA1H (calcium voltage-gated channel subunit alpha1 H). [provided by Alliance of Genome Resources, Apr 2022]

Cacna1h Products(1)

mRNA	Protein	Name
NM_153814.2	NP_722521.1	voltage-dependent T-type calcium channel subunit alpha-1H

Gene Ontology

Molecular Function
Biological Process
Cellular Component

Molecular Function GO Annotation	Evidence	Reference	Source
enables low voltage-gated calcium channel activity	IDA IDA: Inferred from direct assay	11073957	RGD

Biological Process GO Annotation	Evidence	Reference	Source
involved in aldosterone biosynthetic process	IMP IMP: Inferred from mutant phenotype	19342457	RGD
involved in calcium ion import	IDA IDA: Inferred from direct assay	16935432	RGD
involved in calcium ion import	IMP IMP: Inferred from mutant phenotype	19443576	RGD
involved in calcium ion transport	IDA IDA: Inferred from direct assay	11073957	RGD
involved in cortisol biosynthetic process	IMP IMP: Inferred from mutant phenotype	19342457	RGD
involved in positive regulation of cardiac muscle cell contraction	IMP IMP: Inferred from mutant phenotype	19443576	RGD

Cellular Component GO Annotation	Evidence	Reference	Source
located in dendrite	IDA IDA: Inferred from direct assay	16736476	RGD
located in perikaryon	IDA IDA: Inferred from direct assay	16736476	RGD

EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

Protein Preferred Names

Protein Names

voltage-dependent T-type calcium channel subunit alpha-1H

calcium channel, voltage-dependent, T type, alpha 1H subunit

voltage-gated calcium channel subunit alpha Cav3.2

Related Agents

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS01798	CACNA1H Human Pre-designed siRNA Set A	Pre-designed Set	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Homo sapiens	Cacna1h	NCBI	NCBI:8912

Name
Email *

	Sorry, but the email address you supplied was invalid.