Adcy6 - adenylate cyclase 6 Gene

Also Known as AC6; mKIAA0422

Species: Mus musculus

Gene Type: protein coding
Gene ID: 11512

Summary

Enables calcium- and calmodulin-responsive Adenylate Cyclase activity and scaffold protein binding activity. Involved in several processes, including cAMP biosynthetic process; cellular response to forskolin; and cellular response to vasopressin. Is intrinsic component of plasma membrane. Is expressed in several structures, including adipose tissue; alimentary system; brain; cardiovascular system; and genitourinary system. Human ortholog(s) of this gene implicated in lethal congenital contracture syndrome. Orthologous to human ADCY6 (Adenylate Cyclase 6). [provided by Alliance of Genome Resources, Apr 2022]

Adcy6 Products (9)

mRNA Protein Name
NM_001368413.2 NP_001355342.1 adenylate cyclase type 6 isoform 2
NM_001410361.1 NP_001397290.1 adenylate cyclase type 6 isoform 2
NM_001410362.1 NP_001397291.1 adenylate cyclase type 6 isoform 3
NM_001410363.1 NP_001397292.1 adenylate cyclase type 6 isoform 4
NM_001410364.1 NP_001397293.1 adenylate cyclase type 6 isoform 2
NM_001410365.1 NP_001397294.1 adenylate cyclase type 6 isoform 5
NM_001410366.1 NP_001397295.1 adenylate cyclase type 6 isoform 6
NM_001410367.1 NP_001397296.1 adenylate cyclase type 6 isoform 7
NM_001410368.1 NP_001397297.1 adenylate cyclase type 6 isoform 8

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables adenylate cyclase activity IDA
IDA: Inferred from direct assay
17593019 MGI
enables adenylate cyclase activity IMP
IMP: Inferred from mutant phenotype
20466003 MGI
enables calcium- and calmodulin-responsive adenylate cyclase activity IDA
IDA: Inferred from direct assay
1379717 MGI
enables scaffold protein binding IPI
IPI: Inferred from physical interaction
20164376 MGI
Biological Process GO Annotation Evidence References Source
involved in adenylate cyclase-activating G protein-coupled receptor signaling pathway IMP
IMP: Inferred from mutant phenotype
20466003 MGI
involved in cAMP biosynthetic process IMP
IMP: Inferred from mutant phenotype
20466003 MGI
involved in cellular response to forskolin IMP
IMP: Inferred from mutant phenotype
20466003 MGI
involved in cellular response to vasopressin IMP
IMP: Inferred from mutant phenotype
20466003 MGI
involved in negative regulation of neuron projection development IMP
IMP: Inferred from mutant phenotype
21986494 MGI
involved in negative regulation of urine volume IMP
IMP: Inferred from mutant phenotype
20466003 MGI
involved in renal water homeostasis IMP
IMP: Inferred from mutant phenotype
20466003 MGI
Cellular Component GO Annotation Evidence References Source
located in plasma membrane IDA
IDA: Inferred from direct assay
20466003 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

adenylate cyclase type 6

  • ATP pyrophosphate-lyase 6

  • adenylate cyclase type VI

  • adenylyl cyclase 6

  • ca(2+)-inhibitable adenylyl cyclase

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS00332 ADCY6 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Adcy6 NCBI NCBI:112