Avil - advillin Gene

Also Known as DOC6; Advil

Species: Mus musculus

Gene Type: protein coding
Gene ID: 11567

Summary

Predicted to enable Arp2/3 complex binding activity; actin filament binding activity; and phosphatidylinositol-4,5-bisphosphate binding activity. Involved in positive regulation of neuron projection development. Predicted to be located in several cellular components, including actin filament; focal adhesion; and lamellipodium. Predicted to be active in actin Cytoskeleton and cytoplasm. Is expressed in several structures, including eye; forelimb; nervous system; skin; and tongue papillae. Human ortholog(s) of this gene implicated in nephrotic syndrome type 21. Orthologous to human AVIL (advillin). [provided by Alliance of Genome Resources, Apr 2022]

Avil Products (2)

mRNA Protein Name
NM_001402490.1 NP_001389419.1 advillin
NM_009635.4 NP_033765.2 advillin

Gene Ontology

  • Molecular Function
  • Biological Process
Molecular Function GO Annotation Evidence References Source
enables protein binding IPI
IPI: Inferred from physical interaction
15247299 MGI
Biological Process GO Annotation Evidence References Source
involved in positive regulation of neuron projection development IDA
IDA: Inferred from direct assay
15247299 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

advillin

  • actin-binding protein DOC6

  • p92

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (5)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-164677 PLH1215 Inhibitor 99.98% Unkown
HY-RS01278 AVIL Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-164676 PLH2058 / Unkown
HY-RS21297 Avil Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS27816 Avil Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Avil NCBI NCBI:10677