MRGPRF - MAS related GPR family member F Gene

Homo sapiens

Also known as RTA; MRGF; GPR140; GPR168

Gene ID: 116535 | Gene type: protein coding

About MRGPRF

Cytogenetic location: 11q13.3 Genomic coordinates (GRCh38): 11:69,004,398-69,013,633 (from NCBI)

This gene has 3 transcripts (splice variants), 278 orthologues and 10 paralogues. Broad expression in endometrium (RPKM 20.4), prostate (RPKM 13.8) and 18 other tissues.

Summary

Predicted to enable G protein-coupled receptor activity. Predicted to be involved in G protein-coupled receptor signaling pathway. Located in nuclear membrane and plasma membrane. [provided by Alliance of Genome Resources, Apr 2022]

MRGPRF Products(2)

mRNA	Protein	Name
NM_001098515.2	NP_001091985.1	mas-related G-protein coupled receptor member F
NM_145015.5	NP_659452.3	mas-related G-protein coupled receptor member F

MRGPRF Protein Structure

7tm_1

0
100
200
300
343 a.a.

Protein Preferred Names

Protein Names

mas-related G-protein coupled receptor member F

G protein-coupled receptor MrgF

Related Diseases

Diseases

Alias

Isolated Growth Hormone Deficiency, Type Ib

Isolated Growth Hormone Deficiency Type Ib	IGHD1B
Ighd Ib	Growth Hormone Deficiency, Isolated, Type Ib
Congenital Ighd Type Ib	Congenital Isolated Gh Deficiency Type Ib
Congenital Isolated Growth Hormone Deficiency Type Ib	Dwarfism Of Sindh
Pituitary Dwarfism I	Isolated Growth Hormone Deficiency Type 1b
Ighd 1b	Growth Hormone Deficiency, Isolated, 1b

Diseases	Alias
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Related Agents

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS08649	MRGPRF Human Pre-designed siRNA Set A		/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Mus musculus	MRGPRF	MGD	MGI:2384823
Bos taurus	MRGPRF	VGNC	VGNC:31603
Macaca mulatta	MRGPRF	VGNC	VGNC:101355
Felis catus	MRGPRF	VGNC	VGNC:63580
Rattus norvegicus	MRGPRF	RGD	RGD:708478
Canis familiaris	MRGPRF	VGNC	VGNC:43363

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