Slc17a7 - solute carrier family 17 member 7 Gene

Also Known as BNPI; Vglut1

Species: Rattus norvegicus

Gene Type: protein coding
Gene ID: 116638

Summary

Enables inorganic phosphate transmembrane transporter activity and sodium:phosphate symporter activity. Involved in several processes, including neurotransmitter loading into synaptic vesicle; phosphate ion transport; and regulation of synaptic vesicle endocytosis. Located in excitatory synapse and presynaptic active zone. Is integral component of synaptic vesicle membrane. Is active in synaptic vesicle membrane. Biomarker of sciatic neuropathy and transient cerebral ischemia. Orthologous to human SLC17A7 (solute carrier family 17 member 7). [provided by Alliance of Genome Resources, Apr 2022]

Slc17a7 Products (1)

mRNA Protein Name
NM_053859.4 NP_446311.1 vesicular glutamate transporter 1

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence Références Source
enables L-glutamate transmembrane transporter activity IDA
IDA: Inferred from direct assay
19169251 RGD
enables L-glutamate uniporter activity IDA
IDA: Inferred from direct assay
10938000 RGD
enables chloride channel activity IDA
IDA: Inferred from direct assay
10938000 RGD
enables phosphate ion uniporter activity IDA
IDA: Inferred from direct assay
29642010 RGD
enables potassium:proton antiporter activity IDA
IDA: Inferred from direct assay
25433636 RGD
enables protein binding IPI
IPI: Inferred from physical interaction
16815333 RGD
enables sodium:phosphate symporter activity IDA
IDA: Inferred from direct assay
29642010 RGD
Biological Process GO Annotation Evidence Références Source
involved in L-glutamate transmembrane transport IDA
IDA: Inferred from direct assay
10938000 RGD
involved in chloride transport IDA
IDA: Inferred from direct assay
10938000 RGD
involved in neural retina development IEP
IEP: Inferred from expression pattern
18482716 RGD
involved in phosphate ion homeostasis IDA
IDA: Inferred from direct assay
33440152 RGD
involved in phosphate ion transport IDA
IDA: Inferred from direct assay
8202535 RGD
involved in potassium ion transport IDA
IDA: Inferred from direct assay
25433636 RGD
involved in regulation of synaptic vesicle endocytosis IMP
IMP: Inferred from mutant phenotype
16815333 RGD
involved in sodium-dependent phosphate transport IDA
IDA: Inferred from direct assay
29642010 RGD
Cellular Component GO Annotation Evidence Références Source
located in excitatory synapse IDA
IDA: Inferred from direct assay
16519671 RGD
located in presynaptic active zone IDA
IDA: Inferred from direct assay
24613359 RGD
located in synapse IDA
IDA: Inferred from direct assay
15681343 RGD
is active in synaptic vesicle membrane IDA
IDA: Inferred from direct assay
18502731 RGD
located in synaptic vesicle membrane IDA
IDA: Inferred from direct assay
29642010 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

vesicular glutamate transporter 1

  • brain-specific Na(+)-dependent inorganic phosphate cotransporter

  • brain-specific Na-dependent inorganic phosphate cotransporter

  • solute carrier family 17 (sodium-dependent inorganic phosphate cotransporter), member 7

  • solute carrier family 17 (vesicular g

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Nom du produit
Effect
Pureté
Rare Diseases
HY-RS13040 SLC17A7 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Slc17a7 NCBI NCBI:57030