2. Gene
  3. Phox2a - paired-like homeobox 2a Gene

Phox2a - paired-like homeobox 2a Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Rattus norvegicus

Also known as Arix

Gene ID: 116648 | Gene type: protein coding

About Phox2a

Summary

Enables RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Involved in aging and positive regulation of transcription by RNA polymerase II. Predicted to be located in chromatin and nucleus. Human ortholog(s) of this gene implicated in congenital fibrosis of the extraocular muscles 2. Orthologous to human PHOX2A (paired like homeobox 2A). [provided by Alliance of Genome Resources, Apr 2022]

Phox2a Products(1)

mRNA Protein Name
NM_053869.2 NP_446321.2 paired mesoderm homeobox protein 2A
Gene Ontology
  • Molecular Function
  • Biological Process
Molecular Function GO Annotation Evidence Reference Source
enables RNA polymerase II cis-regulatory region sequence-specific DNA binding IDA
IDA: Inferred from direct assay
8613746 RGD
Biological Process GO Annotation Evidence Reference Source
involved in positive regulation of transcription by RNA polymerase II IDA
IDA: Inferred from direct assay
8613746 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

paired mesoderm homeobox protein 2A

ARIX1 homeodomain protein

aristaless homeobox protein homolog

Related Agents

Pre-clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS10451 PHOX2A Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Phox2a NCBI NCBI:401