Dync1i2 - dynein cytoplasmic 1 intermediate chain 2 Gene

Also Known as Dnci2; Dncic2

Species: Rattus norvegicus

Gene Type: protein coding
Gene ID: 116659

Summary

Predicted to enable dynein heavy chain binding activity and dynein light chain binding activity. Involved in brain development; cellular response to nerve growth factor stimulus; and negative regulation of neuron projection development. Located in cytoplasm. Orthologous to human DYNC1I2 (dynein cytoplasmic 1 intermediate chain 2). [provided by Alliance of Genome Resources, Apr 2022]

Dync1i2 Products (3)

mRNA Protein Name
NM_001270624.1 NP_001257553.1 cytoplasmic dynein 1 intermediate chain 2 isoform 2
NM_001270625.1 NP_001257554.1 cytoplasmic dynein 1 intermediate chain 2 isoform 3
NM_053880.2 NP_446332.2 cytoplasmic dynein 1 intermediate chain 2 isoform 1

Gene Ontology

  • Molecular Function
  • Biological Process
Molecular Function GO Annotation Evidence References Source
enables protein-containing complex binding IPI
IPI: Inferred from physical interaction
8522607 RGD
Biological Process GO Annotation Evidence References Source
involved in cellular response to nerve growth factor stimulus IEP
IEP: Inferred from expression pattern
11536324 RGD
involved in negative regulation of neuron projection development IMP
IMP: Inferred from mutant phenotype
23358504 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

cytoplasmic dynein 1 intermediate chain 2

  • DH IC-2

  • cytoplasmic dynein intermediate chain 2

  • dynein intermediate chain 2, cytosolic

  • dynein, cytoplasmic, intermediate chain 2

  • dynein, cytoplasmic, intermediate polypeptide 2

  • oncofetal protein (OFP)

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS04084 DYNC1I2 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Dync1i2 NCBI NCBI:1781