Mta3 - metastasis associated 3 Gene

Also Known as mKIAA1266; 1110002J22Rik

Species: Mus musculus

Gene Type: protein coding
Gene ID: 116871

Summary

Predicted to enable histone deacetylase binding activity; transcription coactivator activity; and transcription corepressor activity. Acts upstream of or within positive regulation of G2/M transition of mitotic cell cycle and positive regulation of cell population proliferation. Located in cytoplasm and nucleus. Is expressed in brain; early conceptus; genitourinary system; and limb. Orthologous to human MTA3 (metastasis associated 1 family member 3). [provided by Alliance of Genome Resources, Apr 2022]

Mta3 Products (9)

mRNA Protein Name
NM_001171052.1 NP_001164523.1 metastasis-associated protein MTA3 isoform 1
NM_001171053.1 NP_001164524.1 metastasis-associated protein MTA3 isoform 3
NM_001171054.1 NP_001164525.1 metastasis-associated protein MTA3 isoform 4
NM_001379388.1 NP_001366317.1 metastasis-associated protein MTA3 isoform 5
NM_001379389.1 NP_001366318.1 metastasis-associated protein MTA3 isoform 5
NM_001379390.1 NP_001366319.1 metastasis-associated protein MTA3 isoform 6
NM_001379391.1 NP_001366320.1 metastasis-associated protein MTA3 isoform 6
NM_001379392.1 NP_001366321.1 metastasis-associated protein MTA3 isoform 7
NM_054082.2 NP_473423.1 metastasis-associated protein MTA3 isoform 2

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables protein binding IPI
IPI: Inferred from physical interaction
21931736 MGI
enables protein-containing complex binding IDA
IDA: Inferred from direct assay
22075476 MGI
Biological Process GO Annotation Evidence References Source
acts upstream of G2/M transition of mitotic cell cycle IMP
IMP: Inferred from mutant phenotype
22075476 MGI
acts upstream of cell population proliferation IMP
IMP: Inferred from mutant phenotype
22075476 MGI
acts upstream of granulosa cell proliferation IMP
IMP: Inferred from mutant phenotype
22075476 MGI
acts upstream of or within positive regulation of G2/M transition of mitotic cell cycle IMP
IMP: Inferred from mutant phenotype
22075476 MGI
acts upstream of or within positive regulation of granulosa cell proliferation IMP
IMP: Inferred from mutant phenotype
22075476 MGI
Cellular Component GO Annotation Evidence References Source
located in cytoplasm IDA
IDA: Inferred from direct assay
11483358 MGI
located in nucleus IDA
IDA: Inferred from direct assay
11483358 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

metastasis-associated protein MTA3

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS08748 MTA3 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Mta3 NCBI NCBI:57504