Slc19a2 - solute carrier family 19 (thiamine transporter), member 2 Gene

Also Known as DDA1; TRMA; THTR1; ThTr-1

Species: Mus musculus

Gene Type: protein coding
Gene ID: 116914

Summary

Enables thiamine transmembrane transporter activity. Involved in thiamine transmembrane transport. Acts upstream of or within thiamine transport. Located in plasma membrane. Is expressed in embryo; liver; and skeletal muscle. Used to study thiamine-responsive megaloblastic anemia syndrome. Human ortholog(s) of this gene implicated in diabetes mellitus; megaloblastic anemia; and thiamine-responsive megaloblastic anemia syndrome. Orthologous to human SLC19A2 (solute carrier family 19 member 2). [provided by Alliance of Genome Resources, Apr 2022]

Slc19a2 Products (2)

mRNA Protein Name
NM_001276455.1 NP_001263384.1 thiamine transporter 1 isoform b
NM_054087.3 NP_473428.1 thiamine transporter 1 isoform a

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables thiamine transmembrane transporter activity IDA
IDA: Inferred from direct assay
11481326 MGI
enables thiamine transmembrane transporter activity IMP
IMP: Inferred from mutant phenotype
12393806 MGI
Biological Process GO Annotation Evidence References Source
involved in pyridoxine transport IDA
IDA: Inferred from direct assay
35512554 MGI
involved in spermatogenesis IMP
IMP: Inferred from mutant phenotype
14567973 MGI
involved in thiamine diphosphate biosynthetic process IDA
IDA: Inferred from direct assay
8186267 MGI
involved in thiamine transmembrane transport IDA
IDA: Inferred from direct assay
24961373 MGI
involved in thiamine transmembrane transport IMP
IMP: Inferred from mutant phenotype
19879271 MGI
acts upstream of or within thiamine transport IDA
IDA: Inferred from direct assay
11481326 MGI
involved in thiamine transport IDA
IDA: Inferred from direct assay
11592824 MGI
involved in thiamine transport IMP
IMP: Inferred from mutant phenotype
12393806 MGI
Cellular Component GO Annotation Evidence References Source
is active in plasma membrane IDA
IDA: Inferred from direct assay
22194418 MGI
located in plasma membrane IDA
IDA: Inferred from direct assay
11481326 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

thiamine transporter 1

  • solute carrier family 19 member 2

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS13048 SLC19A2 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Slc19a2 NCBI NCBI:10560