MCF2L - Mcf2l MCF.2 cell line derived transforming sequence-like Gene

Also Known as Ost; mcf 2l

Species: Rattus norvegicus

Gene Type: protein coding
Gene ID: 117020

Summary

Enables guanyl-nucleotide exchange factor activity. Involved in positive regulation of Rho protein signal transduction. Located in cytoplasm. Is extrinsic component of membrane. Orthologous to human MCF2L (MCF.2 cell line derived transforming sequence like). [provided by Alliance of Genome Resources, Apr 2022]

MCF2L Products (2)

mRNA Protein Name
NM_001413769.1 NP_001400698.1 guanine nucleotide exchange factor DBS isoform 2
NM_053951.2 NP_446403.2 guanine nucleotide exchange factor DBS isoform 1

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables guanyl-nucleotide exchange factor activity IDA
IDA: Inferred from direct assay
7957046 RGD
Biological Process GO Annotation Evidence References Source
involved in intracellular signal transduction IDA
IDA: Inferred from direct assay
7957046 RGD
Cellular Component GO Annotation Evidence References Source
located in cytoplasm IDA
IDA: Inferred from direct assay
7957046 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

guanine nucleotide exchange factor DBS

  • DBL's big sister

  • MCF2-transforming sequence-like protein

  • OST oncogene

  • mcf.2 transforming sequence-like

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (2)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS08223 MCF2L Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS22629 Mcf2l Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens MCF2L NCBI NCBI:23263