Ptf1a - pancreas associated transcription factor 1a Gene

Species: Rattus norvegicus

Gene Type: protein coding
Gene ID: 117034

Summary

Enables RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Involved in exocrine pancreas development and regulation of transcription, DNA-templated. Located in cytoplasm and nucleus. Part of transcription regulator complex. Human ortholog(s) of this gene implicated in pancreatic agenesis. Orthologous to human PTF1A (pancreas associated transcription factor 1a). [provided by Alliance of Genome Resources, Apr 2022]

Ptf1a Products (1)

mRNA Protein Name
NM_053964.2 NP_446416.1 pancreas transcription factor 1 subunit alpha

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables DNA binding IDA
IDA: Inferred from direct assay
2788241 RGD
enables RNA polymerase II cis-regulatory region sequence-specific DNA binding IDA
IDA: Inferred from direct assay
1840677 RGD
Biological Process GO Annotation Evidence References Source
involved in exocrine pancreas development IDA
IDA: Inferred from direct assay
10768861 RGD
involved in regulation of DNA-templated transcription IDA
IDA: Inferred from direct assay
2788241 RGD
Cellular Component GO Annotation Evidence References Source
located in cytoplasm IDA
IDA: Inferred from direct assay
1720355 RGD
located in nucleus IDA
IDA: Inferred from direct assay
1720355 RGD
part of transcription regulator complex IDA
IDA: Inferred from direct assay
1720355 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

pancreas transcription factor 1 subunit alpha

  • PTF1-p48

  • bHLH transcription factor p48

  • p48 DNA-binding subunit of transcription factor PTF1

  • pancreas specific transcription factor, 1a

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS11367 PTF1A Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Ptf1a NCBI NCBI:256297