2. Gene
  3. Kcnj12 - potassium inwardly-rectifying channel, subfamily J, member 12 Gene

Kcnj12 - potassium inwardly-rectifying channel, subfamily J, member 12 Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Rattus norvegicus

Also known as IRK2; Kir2.1; Kir2.2

Gene ID: 117052 | Gene type: protein coding

About Kcnj12

Summary

Enables PDZ domain binding activity. Predicted to be involved in potassium ion import across plasma membrane; protein homotetramerization; and regulation of ion transmembrane transport. Located in T-tubule; dendrite; and neuronal cell body. Orthologous to human KCNJ12 (potassium inwardly rectifying channel subfamily J member 12) and KCNJ18 (potassium inwardly rectifying channel subfamily J member 18). [provided by Alliance of Genome Resources, Apr 2022]

Kcnj12 Products(1)

mRNA Protein Name
NM_053981.2 NP_446433.2 ATP-sensitive inward rectifier potassium channel 12
Gene Ontology
  • Molecular Function
  • Cellular Component
Molecular Function GO Annotation Evidence Reference Source
enables PDZ domain binding IPI
IPI: Inferred from physical interaction
11181181 RGD
enables protein binding IPI
IPI: Inferred from physical interaction
14960569 RGD
Cellular Component GO Annotation Evidence Reference Source
located in T-tubule IDA
IDA: Inferred from direct assay
11181181 RGD
located in dendrite IDA
IDA: Inferred from direct assay
12591157 RGD
located in neuronal cell body IDA
IDA: Inferred from direct assay
12591157 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

ATP-sensitive inward rectifier potassium channel 12

IRK-2

inward rectifier K(+) channel Kir2.2

potassium channel, inwardly rectifying subfamily J member 12

potassium voltage-gated channel subfamily J member 12

Related Agents

Pre-clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS07139 KCNJ12 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Kcnj12 NCBI NCBI:3768