2. Gene
  3. Serpinb7 - serpin family B member 7 Gene

Serpinb7 - serpin family B member 7 Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Rattus norvegicus

Also known as Megsin

Gene ID: 117092 | Gene type: protein coding

About Serpinb7

Summary

Predicted to enable serine-type endopeptidase inhibitor activity. Involved in positive regulation of Collagen biosynthetic process; positive regulation of cytokine production; and positive regulation of glomerular mesangial cell proliferation. Predicted to be active in extracellular space. Biomarker of nephritis. Human ortholog(s) of this gene implicated in IgA glomerulonephritis and familial encephalopathy with neuroserpin inclusion bodies. Orthologous to human SERPINB7 (Serpin family B member 7). [provided by Alliance of Genome Resources, Apr 2022]

Serpinb7 Products(1)

mRNA Protein Name
NM_130404.2 NP_569088.2 serpin B7
Gene Ontology
  • Biological Process
Biological Process GO Annotation Evidence Reference Source
involved in positive regulation of collagen biosynthetic process IMP
IMP: Inferred from mutant phenotype
21945418 RGD
involved in positive regulation of glomerular mesangial cell proliferation IMP
IMP: Inferred from mutant phenotype
21945418 RGD
involved in positive regulation of platelet-derived growth factor production IMP
IMP: Inferred from mutant phenotype
21945418 RGD
involved in positive regulation of transforming growth factor beta1 production IMP
IMP: Inferred from mutant phenotype
21945418 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

serpin B7

serine (or cysteine) peptidase inhibitor, clade B, member 7

serine (or cysteine) proteinase inhibitor, clade B (ovalbumin), member 7

serine (or cysteine) proteinase inhibitor, clade B, member 7

serpin peptidase inhibitor, clade B (ovalbumin), member 7

Related Agents

Pre-clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS12715 SERPINB7 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Serpinb7 NCBI NCBI:8710