Serpinb7 - serpin family B member 7 Gene

Also Known as Megsin

Species: Rattus norvegicus

Gene Type: protein coding
Gene ID: 117092

Summary

Predicted to enable serine-type endopeptidase inhibitor activity. Involved in positive regulation of Collagen biosynthetic process; positive regulation of cytokine production; and positive regulation of glomerular mesangial cell proliferation. Predicted to be active in extracellular space. Biomarker of nephritis. Human ortholog(s) of this gene implicated in IgA glomerulonephritis and familial encephalopathy with neuroserpin inclusion bodies. Orthologous to human SERPINB7 (Serpin family B member 7). [provided by Alliance of Genome Resources, Apr 2022]

Serpinb7 Products (1)

mRNA Protein Name
NM_130404.2 NP_569088.2 serpin B7

Gene Ontology

  • Biological Process
Biological Process GO Annotation Evidence References Source
involved in positive regulation of collagen biosynthetic process IMP
IMP: Inferred from mutant phenotype
21945418 RGD
involved in positive regulation of glomerular mesangial cell proliferation IMP
IMP: Inferred from mutant phenotype
21945418 RGD
involved in positive regulation of platelet-derived growth factor production IMP
IMP: Inferred from mutant phenotype
21945418 RGD
involved in positive regulation of transforming growth factor beta1 production IMP
IMP: Inferred from mutant phenotype
21945418 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

serpin B7

  • serine (or cysteine) peptidase inhibitor, clade B, member 7

  • serine (or cysteine) proteinase inhibitor, clade B (ovalbumin), member 7

  • serine (or cysteine) proteinase inhibitor, clade B, member 7

  • serpin peptidase inhibitor, clade B (ovalbumin), member 7

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS12715 SERPINB7 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Serpinb7 NCBI NCBI:8710