2. Gene
  3. Bhlhe41 - basic helix-loop-helix family, member e41 Gene

Bhlhe41 - basic helix-loop-helix family, member e41 Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Rattus norvegicus

Also known as Dec2; Bhlhb3; Sharp1; SHARP-1

Gene ID: 117095 | Gene type: protein coding

About Bhlhe41

Summary

This gene encodes a basic helix-loop-helix protein expressed in various tissues. The encoded protein can interact with Arntl or compete for E-box binding sites in the promoter of Per1 and repress Clock/Arntl's transactivation of Per1. This gene is believed to be involved in the control of circadian rhythm and cell differentiation. Defects in this gene are associated with the short sleep phenotype. [provided by RefSeq, Feb 2014]

Bhlhe41 Products(1)

mRNA Protein Name
NM_133303.2 NP_579837.2 class E basic helix-loop-helix protein 41
Gene Ontology
  • Biological Process
Biological Process GO Annotation Evidence Reference Source
involved in circadian rhythm IEP
IEP: Inferred from expression pattern
12397359 RGD
involved in regulation of neuronal synaptic plasticity IEP
IEP: Inferred from expression pattern
9532582 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

class E basic helix-loop-helix protein 41

basic helix-loop-helix domain containing, class B3

enhancer-of-split and hairy-related protein 1

Related Agents

Pre-clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS01494 BHLHE41 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Bhlhe41 NCBI NCBI:79365