Nlgn2 - neuroligin 2 Gene

Predicted to enable several functions, including cell adhesion molecule binding activity; identical protein binding activity; and neurexin family protein binding activity. Involved in several processes, including positive regulation of protein localization; presynapse organization; and regulation of synapse assembly. Acts upstream of or within synapse organization. Located in several cellular components, including dendritic shaft; inhibitory synapse; and ribbon synapse. Is integral component of postsynaptic membrane. Is active in GABA-ergic synapse. Is integral component of postsynaptic specialization membrane. Biomarker of sciatic neuropathy and status epilepticus. Orthologous to human NLGN2 (neuroligin 2). [provided by Alliance of Genome Resources, Apr 2022]