2. Gene
  3. SLC6A7 - Slc6a7 solute carrier family 6 member 7 Gene

SLC6A7 - Slc6a7 solute carrier family 6 member 7 Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Rattus norvegicus

Also known as Prot

Gene ID: 117100 | Gene type: protein coding

About SLC6A7

Summary

Enables L-proline transmembrane transporter activity. Involved in proline transport. Is active in Schaffer collateral - CA1 synapse and glutamatergic synapse. Is integral component of presynaptic membrane and integral component of synaptic vesicle membrane. Orthologous to human SLC6A7 (solute carrier family 6 member 7). [provided by Alliance of Genome Resources, Apr 2022]

SLC6A7 Products(1)

mRNA Protein Name
NM_053996.2 NP_446448.2 sodium-dependent proline transporter
Gene Ontology
  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence Reference Source
enables L-proline transmembrane transporter activity IDA
IDA: Inferred from direct assay
1350201 RGD
enables proline:sodium symporter activity IDA
IDA: Inferred from direct assay
10414958 RGD
Biological Process GO Annotation Evidence Reference Source
involved in proline transport IDA
IDA: Inferred from direct assay
1350201 RGD
involved in protein catabolic process EXP
EXP: Inferred from Experiment
6286882 RGD
Cellular Component GO Annotation Evidence Reference Source
is active in Schaffer collateral - CA1 synapse IDA
IDA: Inferred from direct assay
9870934 RGD
is active in glutamatergic synapse IDA
IDA: Inferred from direct assay
9870934 RGD
is active in presynaptic membrane IDA
IDA: Inferred from direct assay
9870934 RGD
is active in synapse EXP
EXP: Inferred from Experiment
6286882 RGD
is active in synaptic vesicle membrane IDA
IDA: Inferred from direct assay
9870934 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

sodium-dependent proline transporter

L-proline transporter

proline transporter

sodium-dependent proline transporter-like

solute carrier family 6 (neurotransmitter transporter), member 7

solute carrier family 6 (neurotransmitter transporter, L-proline), member 7

Related Agents

Clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Phase
HY-113745 LX-6171 Inhibitor / Phase 2
Pre-clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS13318 SLC6A7 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens SLC6A7 NCBI NCBI:6534