SLC6A7 - Slc6a7 solute carrier family 6 member 7 Gene

Also Known as Prot

Species: Rattus norvegicus

Gene Type: protein coding
Gene ID: 117100

Summary

Enables L-proline transmembrane transporter activity. Involved in proline transport. Is active in Schaffer collateral - CA1 synapse and glutamatergic synapse. Is integral component of presynaptic membrane and integral component of synaptic vesicle membrane. Orthologous to human SLC6A7 (solute carrier family 6 member 7). [provided by Alliance of Genome Resources, Apr 2022]

SLC6A7 Products (1)

mRNA Protein Name
NM_053996.2 NP_446448.2 sodium-dependent proline transporter

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables L-proline transmembrane transporter activity IDA
IDA: Inferred from direct assay
1350201 RGD
enables proline:sodium symporter activity IDA
IDA: Inferred from direct assay
10414958 RGD
Biological Process GO Annotation Evidence References Source
involved in proline transport IDA
IDA: Inferred from direct assay
1350201 RGD
involved in protein catabolic process EXP
EXP: Inferred from Experiment
6286882 RGD
Cellular Component GO Annotation Evidence References Source
is active in Schaffer collateral - CA1 synapse IDA
IDA: Inferred from direct assay
9870934 RGD
is active in glutamatergic synapse IDA
IDA: Inferred from direct assay
9870934 RGD
is active in presynaptic membrane IDA
IDA: Inferred from direct assay
9870934 RGD
is active in synapse EXP
EXP: Inferred from Experiment
6286882 RGD
is active in synaptic vesicle membrane IDA
IDA: Inferred from direct assay
9870934 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

sodium-dependent proline transporter

  • L-proline transporter

  • proline transporter

  • sodium-dependent proline transporter-like

  • solute carrier family 6 (neurotransmitter transporter), member 7

  • solute carrier family 6 (neurotransmitter transporter, L-proline), member 7

Related Agents

  • Clinical Phase
  • Pre-clinical Phase

Clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Phase
HY-113745 LX-6171 Inhibitor 97.09% Phase 2

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS13318 SLC6A7 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens SLC6A7 NCBI NCBI:6534