Ube3b - ubiquitin protein ligase E3B Gene

Species: Mus musculus

Gene Type: protein coding
Gene ID: 117146

Summary

Predicted to enable ubiquitin protein Ligase activity. Predicted to be involved in protein polyubiquitination and ubiquitin-dependent protein catabolic process. Is expressed in several structures, including alimentary system; brain; genitourinary system; respiratory system; and sensory organ. Human ortholog(s) of this gene implicated in Kaufman oculocerebrofacial syndrome. Orthologous to human UBE3B (ubiquitin protein Ligase E3B). [provided by Alliance of Genome Resources, Apr 2022]

Ube3b Products (2)

mRNA Protein Name
NM_001331219.1 NP_001318148.1 ubiquitin-protein ligase E3B isoform 2 precursor
NM_054093.3 NP_473434.2 ubiquitin-protein ligase E3B isoform 1

Gene Ontology

  • Biological Process
  • Cellular Component
Biological Process GO Annotation Evidence References Source
involved in regulation of postsynapse assembly IDA
IDA: Inferred from direct assay
32249816 MGI
involved in regulation of postsynapse assembly IEP
IEP: Inferred from expression pattern
32249816 MGI
involved in regulation of postsynapse assembly IMP
IMP: Inferred from mutant phenotype
32249816 MGI
Cellular Component GO Annotation Evidence References Source
is active in glutamatergic synapse IDA
IDA: Inferred from direct assay
32249816 MGI
is active in glutamatergic synapse IEP
IEP: Inferred from expression pattern
32249816 MGI
is active in glutamatergic synapse IMP
IMP: Inferred from mutant phenotype
32249816 MGI
is active in postsynapse IDA
IDA: Inferred from direct assay
32249816 MGI
is active in postsynapse IEP
IEP: Inferred from expression pattern
32249816 MGI
is active in postsynapse IMP
IMP: Inferred from mutant phenotype
32249816 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

ubiquitin-protein ligase E3B

  • HECT-type ubiquitin transferase E3B

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS15369 UBE3B Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Ube3b NCBI NCBI:89910