Plscr1 - phospholipid scramblase 1 Gene

Species: Rattus norvegicus

Gene Type: protein coding
Gene ID: 117540

Summary

Enables enzyme binding activity. Involved in several processes, including plasma membrane phospholipid scrambling; regulation of Fc receptor mediated stimulatory signaling pathway; and regulation of mast cell activation. Located in membrane raft and plasma membrane. Orthologous to human PLSCR1 (phospholipid scramblase 1). [provided by Alliance of Genome Resources, Apr 2022]

Plscr1 Products (1)

mRNA Protein Name
NM_057194.1 NP_476542.1 phospholipid scramblase 1

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables enzyme binding IPI
IPI: Inferred from physical interaction
18579528 RGD
Biological Process GO Annotation Evidence References Source
involved in immune response IMP
IMP: Inferred from mutant phenotype
11259432 RGD
involved in plasma membrane phospholipid scrambling IMP
IMP: Inferred from mutant phenotype
17712045 RGD
involved in regulation of Fc receptor mediated stimulatory signaling pathway IMP
IMP: Inferred from mutant phenotype
18579528 RGD
involved in regulation of mast cell activation IMP
IMP: Inferred from mutant phenotype
18579528 RGD
Cellular Component GO Annotation Evidence References Source
located in membrane raft IDA
IDA: Inferred from direct assay
18579528 RGD
located in plasma membrane IDA
IDA: Inferred from direct assay
17712045 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

phospholipid scramblase 1

  • PL scramblase 1

  • ca(2+)-dependent phospholipid scramblase 1

  • mg(2+)-dependent nuclease

  • phospholipid scramblase 2

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (3)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS10741 PLSCR1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS18201 Plscr1 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS24677 Plscr1 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Plscr1 NCBI NCBI:5359