Uba3 - ubiquitin-like modifier activating enzyme 3 Gene

Also Known as Ube1c

Species: Rattus norvegicus

Gene Type: protein coding
Gene ID: 117553

Summary

Enables NEDD8 activating enzyme activity and nuclear receptor binding activity. Involved in negative regulation of transcription, DNA-templated. Predicted to be part of protein-containing complex. Predicted to be active in cytoplasm and nucleus. Orthologous to human UBA3 (ubiquitin like modifier activating enzyme 3). [provided by Alliance of Genome Resources, Apr 2022]

Uba3 Products (1)

mRNA Protein Name
NM_057205.2 NP_476553.1 NEDD8-activating enzyme E1 catalytic subunit

Gene Ontology

  • Molecular Function
  • Biological Process
Molecular Function GO Annotation Evidence References Source
enables NEDD8 activating enzyme activity IDA
IDA: Inferred from direct assay
11818503 RGD
enables NEDD8 activating enzyme activity IMP
IMP: Inferred from mutant phenotype
11818503 RGD
enables nuclear receptor binding IPI
IPI: Inferred from physical interaction
11818503 RGD
enables protein-containing complex binding IMP
IMP: Inferred from mutant phenotype
11818503 RGD
Biological Process GO Annotation Evidence References Source
involved in negative regulation of DNA-templated transcription IDA
IDA: Inferred from direct assay
11818503 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

NEDD8-activating enzyme E1 catalytic subunit

  • NEDD8-activating enzyme E1C

  • ubiquitin-activating enzyme 3

  • ubiquitin-activating enzyme E1C (UBA3 homolog, yeast)

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS15321 UBA3 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Uba3 NCBI NCBI:9039