Uba3 - ubiquitin-like modifier activating enzyme 3 Gene

Rattus norvegicus

Also known as Ube1c

Gene ID: 117553 | Gene type: protein coding

About Uba3

Summary

Enables NEDD8 activating enzyme activity and nuclear receptor binding activity. Involved in negative regulation of transcription, DNA-templated. Predicted to be part of protein-containing complex. Predicted to be active in cytoplasm and nucleus. Orthologous to human UBA3 (ubiquitin like modifier activating enzyme 3). [provided by Alliance of Genome Resources, Apr 2022]

Uba3 Products(1)

mRNA	Protein	Name
NM_057205.2	NP_476553.1	NEDD8-activating enzyme E1 catalytic subunit

Gene Ontology

Molecular Function
Biological Process

Molecular Function GO Annotation	Evidence	Reference	Source
enables NEDD8 activating enzyme activity	IDA IDA: Inferred from direct assay	11818503	RGD
enables NEDD8 activating enzyme activity	IMP IMP: Inferred from mutant phenotype	11818503	RGD
enables nuclear receptor binding	IPI IPI: Inferred from physical interaction	11818503	RGD
enables protein-containing complex binding	IMP IMP: Inferred from mutant phenotype	11818503	RGD

Biological Process GO Annotation	Evidence	Reference	Source
involved in negative regulation of DNA-templated transcription	IDA IDA: Inferred from direct assay	11818503	RGD

EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

Protein Preferred Names

Protein Names

NEDD8-activating enzyme E1 catalytic subunit

NEDD8-activating enzyme E1C	ubiquitin-activating enzyme 3
ubiquitin-activating enzyme E1C (UBA3 homolog, yeast)

Related Agents

Pre-clinical Phase

Bioactive Molecules (1)

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS15321	UBA3 Human Pre-designed siRNA Set A	Pre-designed Set	/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Homo sapiens	Uba3	NCBI	NCBI:9039

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