Atp6v1b2 - ATPase H+ transporting V1 subunit B2 Gene

Also Known as Vatb; Atp6b2; Atp6b1b2

Species: Rattus norvegicus

Gene Type: protein coding
Gene ID: 117596

Summary

Predicted to enable ATP binding activity and hydrolase activity. Predicted to be involved in vacuolar acidification. Is integral component of membrane. Part of vacuolar proton-transporting V-type ATPase, V1 domain. Human ortholog(s) of this gene implicated in autosomal dominant congenital deafness with onychodystrophy. Orthologous to human ATP6V1B2 (ATPase H+ transporting V1 subunit B2). [provided by Alliance of Genome Resources, Apr 2022]

Atp6v1b2 Products (1)

mRNA Protein Name
NM_057213.2 NP_476561.1 V-type proton ATPase subunit B, brain isoform

Gene Ontology

  • Cellular Component
Cellular Component GO Annotation Evidence References Source
is active in extrinsic component of synaptic vesicle membrane EXP
EXP: Inferred from Experiment
32165585 RGD
is active in extrinsic component of synaptic vesicle membrane IDA
IDA: Inferred from direct assay
32165585 RGD
part of vacuolar proton-transporting V-type ATPase, V1 domain IDA
IDA: Inferred from direct assay
32165585 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

V-type proton ATPase subunit B, brain isoform

  • ATPase, H transporting, lysosomal V1 subunit B2

  • ATPase, H+ transporting, V1 subunit B

  • ATPase, H+ transporting, lysosomal (vacuolar proton pump), beta 56/58 kDa

  • V-ATPase subunit B 2

  • endomembrane proton pump 58 kDa subunit

  • vacuolar H+ATPase B2

  • vacuola

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS01225 ATP6V1B2 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Atp6v1b2 NCBI NCBI:526