Srgap1 - SLIT-ROBO Rho GTPase activating protein 1 Gene

Also Known as Arhgap13; 4930572H05Rik

Species: Mus musculus

Gene Type: protein coding
Gene ID: 117600

Summary

Enables GTPase activator activity and small GTPase binding activity. Acts upstream of or within Rho protein signal transduction and cell migration. Predicted to be active in cytoplasm. Is expressed in nervous system and s-shaped body. Human ortholog(s) of this gene implicated in thyroid gland papillary carcinoma. Orthologous to human SRGAP1 (SLIT-ROBO Rho GTPase activating protein 1). [provided by Alliance of Genome Resources, Apr 2022]

Srgap1 Products (2)

mRNA Protein Name
NM_001081037.2 NP_001074506.1 SLIT-ROBO Rho GTPase-activating protein 1 isoform 1
NM_001242411.1 NP_001229340.1 SLIT-ROBO Rho GTPase-activating protein 1 isoform 2

Gene Ontology

  • Molecular Function
  • Biological Process
Molecular Function GO Annotation Evidence References Source
enables GTPase activator activity IDA
IDA: Inferred from direct assay
11672528 MGI
enables protein binding IPI
IPI: Inferred from physical interaction
11672528 MGI
enables small GTPase binding IDA
IDA: Inferred from direct assay
11672528 MGI
Biological Process GO Annotation Evidence References Source
acts upstream of or within Rho protein signal transduction IDA
IDA: Inferred from direct assay
11672528 MGI
acts upstream of or within cell migration IDA
IDA: Inferred from direct assay
11672528 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

SLIT-ROBO Rho GTPase-activating protein 1

  • Rho GTPase activating protein 13

  • rho GTPase-activating protein 13

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS13762 SRGAP1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Srgap1 NCBI NCBI:57522