Ap1b1 - adaptor protein complex AP-1, beta 1 subunit Gene

Also Known as Adtb1; b2b1660Clo

Species: Mus musculus

Gene Type: protein coding
Gene ID: 11764

Summary

Enables protein kinase binding activity. Acts upstream of or within determination of left/right symmetry; heart development; and kidney development. Predicted to be located in Golgi apparatus and cytosol. Predicted to be part of clathrin adaptor complex. Is expressed in primary sex cord. Used to study Kartagener syndrome; primary ciliary dyskinesia; and visceral heterotaxy. Orthologous to human AP1B1 (adaptor related protein complex 1 subunit beta 1). [provided by Alliance of Genome Resources, Apr 2022]

Ap1b1 Products (5)

mRNA Protein Name
NM_001243043.1 NP_001229972.1 AP-1 complex subunit beta-1 isoform 1
NM_001243044.1 NP_001229973.1 AP-1 complex subunit beta-1 isoform 3
NM_001355659.1 NP_001342588.1 AP-1 complex subunit beta-1 isoform 1
NM_001355660.1 NP_001342589.1 AP-1 complex subunit beta-1 isoform 4
NM_007454.3 NP_031480.2 AP-1 complex subunit beta-1 isoform 2

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables protein binding IPI
IPI: Inferred from physical interaction
9733768 MGI
enables protein kinase binding IPI
IPI: Inferred from physical interaction
21307259 MGI
Biological Process GO Annotation Evidence References Source
acts upstream of or within determination of left/right symmetry IMP
IMP: Inferred from mutant phenotype
25807483 MGI
acts upstream of or within heart development IMP
IMP: Inferred from mutant phenotype
25807483 MGI
acts upstream of or within kidney development IMP
IMP: Inferred from mutant phenotype
27002738 MGI
Cellular Component GO Annotation Evidence References Source
is active in synaptic vesicle EXP
EXP: Inferred from Experiment
34736896 MGI
is active in synaptic vesicle IDA
IDA: Inferred from direct assay
34736896 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

AP-1 complex subunit beta-1

  • adaptor protein complex AP-1 subunit beta-1

  • adaptor-related protein complex AP-1, beta 1 subunit

  • beta-adaptin 1

  • beta-prime adaptin

  • clathrin assembly protein complex 1 beta large chain

  • golgi adaptor HA1/AP1 adaptin beta subunit

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS00776 AP1B1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Ap1b1 NCBI NCBI:162