Ap3b2 - adaptor-related protein complex 3, beta 2 subunit Gene

Also Known as Naptb; beta3B; [b]-NAP; beta-NAP

Species: Mus musculus

Gene Type: protein coding
Gene ID: 11775

Summary

Involved in anterograde synaptic vesicle transport. Predicted to be located in trans-Golgi network. Predicted to be part of AP-3 adaptor complex. Is expressed in adrenal gland; gut; nervous system; sensory organ; and testis. Human ortholog(s) of this gene implicated in developmental and epileptic encephalopathy 48. Orthologous to human AP3B2 (adaptor related protein complex 3 subunit beta 2). [provided by Alliance of Genome Resources, Apr 2022]

Ap3b2 Products (1)

mRNA Protein Name
NM_021492.3 NP_067467.2 AP-3 complex subunit beta-2

Gene Ontology

  • Biological Process
  • Cellular Component
Biological Process GO Annotation Evidence References Source
involved in anterograde axonal transport IMP
IMP: Inferred from mutant phenotype
21998198 MGI
involved in anterograde synaptic vesicle transport IMP
IMP: Inferred from mutant phenotype
21998198 MGI
involved in synaptic vesicle endocytosis IDA
IDA: Inferred from direct assay
24133283 MGI
involved in synaptic vesicle endocytosis IEP
IEP: Inferred from expression pattern
24133283 MGI
Cellular Component GO Annotation Evidence References Source
is active in presynapse IDA
IDA: Inferred from direct assay
24133283 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

AP-3 complex subunit beta-2

  • AP-3 complex beta-2 subunit

  • adapter-related protein complex 3 subunit beta-2

  • adaptor protein complex AP-3 beta-2 subunit

  • adaptor protein complex AP-3 subunit beta-2

  • adaptor-related protein complex 3 subunit beta-2

  • adaptor-related protein complex AP-3

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS00790 AP3B2 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Ap3b2 NCBI NCBI:8120