Apbb2 - amyloid beta (A4) precursor protein-binding, family B, member 2 Gene

Also Known as TR2L; Zfra; Rirl1; FE65L1; 2310007D03Rik

Species: Mus musculus

Gene Type: protein coding
Gene ID: 11787

Summary

Predicted to enable amyloid-beta binding activity. Involved in maintenance of lens transparency and smooth muscle contraction. Acts upstream of or within extracellular matrix organization; generation of neurons; and regulation of apoptotic process. Located in cytoplasm. Is expressed in several structures, including alimentary system; central nervous system; eye; genitourinary system; and hemolymphoid system gland. Human ortholog(s) of this gene implicated in Alzheimer's disease and cognitive disorder. Orthologous to human APBB2 (amyloid beta precursor protein binding family B member 2). [provided by Alliance of Genome Resources, Apr 2022]

Apbb2 Products (6)

mRNA Protein Name
NM_001201413.1 NP_001188342.1 amyloid beta precursor protein binding family B member 2 isoform 2
NM_001201414.1 NP_001188343.1 amyloid beta precursor protein binding family B member 2 isoform 3
NM_001201415.1 NP_001188344.1 amyloid beta precursor protein binding family B member 2 isoform 4
NM_001201416.1 NP_001188345.1 amyloid beta precursor protein binding family B member 2 isoform 5
NM_001310626.1 NP_001297555.1 amyloid beta precursor protein binding family B member 2 isoform 6
NM_009686.2 NP_033816.1 amyloid beta precursor protein binding family B member 2 isoform 1

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables protein binding IPI
IPI: Inferred from physical interaction
15629131 MGI
Biological Process GO Annotation Evidence References Source
acts upstream of or within axon guidance IGI
IGI: Inferred from genetic interaction
16407979 MGI
acts upstream of or within extracellular matrix organization IGI
IGI: Inferred from genetic interaction
16407979 MGI
involved in maintenance of lens transparency IMP
IMP: Inferred from mutant phenotype
25757569 MGI
acts upstream of or within negative regulation of apoptotic process IGI
IGI: Inferred from genetic interaction
15629131 MGI
acts upstream of or within neuron migration IGI
IGI: Inferred from genetic interaction
16407979 MGI
acts upstream of or within positive regulation of apoptotic process IDA
IDA: Inferred from direct assay
15629131 MGI
involved in smooth muscle contraction IMP
IMP: Inferred from mutant phenotype
25757569 MGI
Cellular Component GO Annotation Evidence References Source
located in cytoplasm IDA
IDA: Inferred from direct assay
15629131 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

amyloid beta precursor protein binding family B member 2

amyloid-beta A4 precursor protein-binding family B member 2

  • protein Fe65-like 1

  • zinc finger-like protein

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS00806 APBB2 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Apbb2 NCBI NCBI:323