Aqp8 - aquaporin 8 Gene

Also Known as AQP-8

Species: Mus musculus

Gene Type: protein coding
Gene ID: 11833

Summary

Predicted to enable water channel activity. Acts upstream of or within water transport. Predicted to be located in intracellular canaliculus and intracellular membrane-bounded organelle. Is expressed in several structures, including alimentary system; diaphragm; early conceptus; genitourinary system; and spleen. Orthologous to human AQP8 (Aquaporin 8). [provided by Alliance of Genome Resources, Apr 2022]

Aqp8 Products (2)

mRNA Protein Name
NM_001109045.1 NP_001102515.1 aquaporin-8 isoform 2
NM_007474.2 NP_031500.1 aquaporin-8 isoform 1

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables ammonium channel activity IMP
IMP: Inferred from mutant phenotype
16624991 MGI
enables urea channel activity IDA
IDA: Inferred from direct assay
9388476 MGI
enables water channel activity IDA
IDA: Inferred from direct assay
9388476 MGI
enables water channel activity IMP
IMP: Inferred from mutant phenotype
15647389 MGI
Biological Process GO Annotation Evidence References Source
involved in B cell differentiation IMP
IMP: Inferred from mutant phenotype
27256569 MGI
involved in ammonium import across plasma membrane IDA
IDA: Inferred from direct assay
16624991 MGI
involved in hydrogen peroxide transmembrane transport IMP
IMP: Inferred from mutant phenotype
27256569 MGI
involved in urea transport IDA
IDA: Inferred from direct assay
9388476 MGI
involved in water transport IDA
IDA: Inferred from direct assay
9388476 MGI
acts upstream of or within water transport IMP
IMP: Inferred from mutant phenotype
15647389 MGI
involved in water transport IMP
IMP: Inferred from mutant phenotype
16624991 MGI
Cellular Component GO Annotation Evidence References Source
located in apical plasma membrane IDA
IDA: Inferred from direct assay
15859952 MGI
located in intracellular canaliculus IDA
IDA: Inferred from direct assay
14512882 MGI
located in intracellular vesicle IDA
IDA: Inferred from direct assay
14512882 MGI
located in mitochondrion IDA
IDA: Inferred from direct assay
14512882 MGI
located in plasma membrane IDA
IDA: Inferred from direct assay
15647389 MGI
located in smooth endoplasmic reticulum IDA
IDA: Inferred from direct assay
14512882 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

aquaporin-8

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS00880 AQP8 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Aqp8 NCBI NCBI:343