2. Gene
  3. Arf4 - ADP-ribosylation factor 4 Gene

Arf4 - ADP-ribosylation factor 4 Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Mus musculus
Gene ID: 11843 | Gene type: protein coding

About Arf4

Summary

Predicted to enable GTP binding activity and epidermal growth factor receptor binding activity. Involved in regulation of postsynapse organization. Acts upstream of or within several processes, including apical protein localization; dendritic spine development; and establishment or maintenance of epithelial cell apical/basal polarity. Located in Golgi apparatus; glutamatergic synapse; and plasma membrane. Is expressed in several structures, including alimentary system; extraembryonic component; nervous system; nose; and skeleton. Orthologous to human ARF4 (ADP ribosylation factor 4). [provided by Alliance of Genome Resources, Apr 2022]

Arf4 Products(1)

mRNA Protein Name
NM_007479.4 NP_031505.1 ADP-ribosylation factor 4
Gene Ontology
  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence Reference Source
enables protein binding IPI
IPI: Inferred from physical interaction
20048263 MGI
Biological Process GO Annotation Evidence Reference Source
acts upstream of or within apical protein localization IMP
IMP: Inferred from mutant phenotype
24586199 MGI
acts upstream of or within dendritic spine development IMP
IMP: Inferred from mutant phenotype
23050017 MGI
acts upstream of or within establishment or maintenance of epithelial cell apical/basal polarity IMP
IMP: Inferred from mutant phenotype
24586199 MGI
acts upstream of or within learning IMP
IMP: Inferred from mutant phenotype
23050017 MGI
acts upstream of or within protein localization to cilium IMP
IMP: Inferred from mutant phenotype
24586199 MGI
involved in regulation of postsynapse organization IDA
IDA: Inferred from direct assay
23050017 MGI
involved in regulation of postsynapse organization IMP
IMP: Inferred from mutant phenotype
23050017 MGI
involved in regulation of synapse organization IDA
IDA: Inferred from direct assay
23050017 MGI
involved in regulation of synapse organization IMP
IMP: Inferred from mutant phenotype
23050017 MGI
Cellular Component GO Annotation Evidence Reference Source
located in Golgi apparatus IDA
IDA: Inferred from direct assay
24586199 MGI
located in cytoplasm IDA
IDA: Inferred from direct assay
8947846 MGI
is active in glutamatergic synapse IDA
IDA: Inferred from direct assay
23050017 MGI
is active in glutamatergic synapse IMP
IMP: Inferred from mutant phenotype
23050017 MGI
located in plasma membrane IDA
IDA: Inferred from direct assay
8947846 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

ADP-ribosylation factor 4

Related Agents

Pre-clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS00896 ARF4 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Arf4 NCBI NCBI:378