2. Gene
  3. Arvcf - armadillo repeat gene deleted in velocardiofacial syndrome Gene

Arvcf - armadillo repeat gene deleted in velocardiofacial syndrome Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Mus musculus
Gene ID: 11877 | Gene type: protein coding

About Arvcf

Summary

Predicted to enable Cadherin binding activity. Predicted to be involved in cell-cell adhesion and cell-cell junction assembly. Predicted to act upstream of or within calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules. Located in cytoplasm; nucleus; and plasma membrane. Is expressed in several structures, including cardiovascular system; central nervous system; forelimb bud; metanephros; and sensory organ. Human ortholog(s) of this gene implicated in DiGeorge syndrome. Orthologous to human ARVCF (ARVCF delta catenin family member). [provided by Alliance of Genome Resources, Apr 2022]

Arvcf Products(6)

mRNA Protein Name
NM_001272028.1 NP_001258957.1 splicing regulator ARVCF isoform 1
NM_001272029.1 NP_001258958.1 splicing regulator ARVCF isoform 2
NM_001272030.1 NP_001258959.1 splicing regulator ARVCF isoform 2
NM_001272031.1 NP_001258960.1 splicing regulator ARVCF isoform 3
NM_001272032.1 NP_001258961.1 splicing regulator ARVCF isoform 4
NM_033474.3 NP_258435.2 splicing regulator ARVCF isoform 1
Gene Ontology
  • Molecular Function
  • Cellular Component
Molecular Function GO Annotation Evidence Reference Source
enables protein binding IPI
IPI: Inferred from physical interaction
11058098 MGI
Cellular Component GO Annotation Evidence Reference Source
located in cytoplasm IDA
IDA: Inferred from direct assay
11719554 MGI
located in nucleus IDA
IDA: Inferred from direct assay
11058098 MGI
located in plasma membrane IDA
IDA: Inferred from direct assay
11058098 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

splicing regulator ARVCF

armadillo repeat protein deleted in velo-cardio-facial syndrome homolog

armadillo repeat gene deleted in velo-cardio-facial syndrome

Related Agents

Pre-clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS01050 ARVCF Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Arvcf NCBI NCBI:421