Arsb - arylsulfatase B Gene

Also Known as As1; As-1; As-1r; As-1s; As-1t; As1-r; As1-s; As1-t; Asr-1; Ast-1; 1110007C02Rik

Species: Mus musculus

Gene Type: protein coding
Gene ID: 11881

Summary

Enables arylsulfatase activity. Acts upstream of or within anterior head development. Located in cell surface. Is expressed in skeleton. Used to study mucopolysaccharidosis VI. Human ortholog(s) of this gene implicated in mucopolysaccharidosis VI. Orthologous to human ARSB (arylsulfatase B). [provided by Alliance of Genome Resources, Apr 2022]

Arsb Products (1)

mRNA Protein Name
NM_009712.3 NP_033842.3 arylsulfatase B precursor

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables N-acetylgalactosamine-6-sulfatase activity IMP
IMP: Inferred from mutant phenotype
24240681 MGI
enables arylsulfatase activity IDA
IDA: Inferred from direct assay
7470017 MGI
Biological Process GO Annotation Evidence References Source
acts upstream of or within anterior head development IMP
IMP: Inferred from mutant phenotype
26234751 MGI
involved in dermatan sulfate catabolic process IMP
IMP: Inferred from mutant phenotype
24240681 MGI
Cellular Component GO Annotation Evidence References Source
located in cell surface IDA
IDA: Inferred from direct assay
19536613 MGI
is active in lysosome IDA
IDA: Inferred from direct assay
30075049 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

arylsulfatase B

  • ASB

  • G4S

  • N-acetylgalactosamine-4-sulfatase

  • arylsulfatase B complex

  • arylsulfatase B regulation

  • arylsulfatase B structural

  • arylsulfatase B temporal regulation

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (4)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-E70186 Arylsulfatase B / Unkown
HY-RS00729 ANKRD44 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS01035 ARSB Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS13385 SLURP1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Arsb NCBI NCBI:411