COMTD1 - catechol-O-methyltransferase domain containing 1 Gene

Species: Homo sapiens

Gene Type: protein coding
Gene ID: 118881

About COMTD1

This gene has 7 transcripts (splice variants), 257 orthologues and 2 paralogues. Broad expression in colon (RPKM 11.0), stomach (RPKM 8.5) and 24 other tissues.

Summary

Predicted to enable S-adenosylmethionine-dependent methyltransferase activity. Predicted to be involved in methylation. Predicted to be integral component of membrane. [provided by Alliance of Genome Resources, Apr 2022]

COMTD1 Products (1)

mRNA Protein Name
NM_144589.4 NP_653190.2 catechol O-methyltransferase domain-containing protein 1

Gene Ontology

  • Molecular Function
Molecular Function GO Annotation Evidence References Source
enables protein binding IPI
IPI: Inferred from physical interaction
25416956 GOA
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

COMTD1 Protein Structure

Methyltransf_3

Methyltransf_3: O-methyltransferase (60 - 261)

  • 0
  • 100
  • 200
  • 262 a.a.
Protein Preferred Names Protein Names

catechol O-methyltransferase domain-containing protein 1

Related Diseases

Diseases Alias
Tatton-Brown-Rahman Syndrome

  • TBRS

  • Dnmt3a Overgrowth Syndrome

  • Tatton-Brown-Rahman Overgrowth Syndrome

  • Dos

  • Dnmt3a-Related Overgrowth Syndrome

  • Doid:0112339

  • Dose
Hematuria, Benign Familial

  • Benign Familial Hematuria

  • BFH

  • Thin Membrane Nephropathy

  • Tmn

  • Thin Basement Membrane Nephropathy

  • Thin-Basement-Membrane Nephropathy

  • Hematuria, Familial Benign

  • Hematuria Benign Familial

  • Hematuria, Benign, Familial

  • Thin Basement Membrane Disease
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS03019 COMTD1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Mus musculus COMTD1 MGD MGI:1916406
Rattus norvegicus COMTD1 RGD RGD:1306581
Bos taurus COMTD1 VGNC VGNC:27591
Macaca mulatta COMTD1 VGNC VGNC:71353
Canis familiaris COMTD1 VGNC VGNC:39502
Felis catus COMTD1 VGNC VGNC:61080
Others COMTD1 NCBI