2. Gene
  3. Astn1 - astrotactin 1 Gene

Astn1 - astrotactin 1 Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Mus musculus

Also known as Astn; GC14; mKIAA0289

Gene ID: 11899 | Gene type: protein coding

About Astn1

Summary

Acts upstream of or within locomotory behavior; neuron cell-cell adhesion; and neuron migration. Located in endosome and external side of plasma membrane. Is integral component of membrane. Is expressed in central nervous system and retina. Orthologous to human ASTN1 (astrotactin 1). [provided by Alliance of Genome Resources, Apr 2022]

Astn1 Products(2)

mRNA Protein Name
NM_001205204.2 NP_001192133.1 astrotactin-1 isoform 1 precursor
NM_007495.5 NP_031521.2 astrotactin-1 isoform 2 precursor
Gene Ontology
  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence Reference Source
enables protein binding IPI
IPI: Inferred from physical interaction
20573900 MGI
Biological Process GO Annotation Evidence Reference Source
acts upstream of or within cell migration IMP
IMP: Inferred from mutant phenotype
11861479 MGI
acts upstream of or within cell-cell adhesion IMP
IMP: Inferred from mutant phenotype
11861479 MGI
acts upstream of or within locomotory behavior IMP
IMP: Inferred from mutant phenotype
11861479 MGI
acts upstream of or within neuron cell-cell adhesion IDA
IDA: Inferred from direct assay
8602532 MGI
acts upstream of or within neuron migration IDA
IDA: Inferred from direct assay
8602532 MGI
acts upstream of or within neuron migration IMP
IMP: Inferred from mutant phenotype
1821847 MGI
Cellular Component GO Annotation Evidence Reference Source
located in endosome IDA
IDA: Inferred from direct assay
20573900 MGI
located in external side of plasma membrane IDA
IDA: Inferred from direct assay
20573900 MGI
located in membrane IDA
IDA: Inferred from direct assay
20573900 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

astrotactin-1

neuronal migration protein GC14

Related Agents

Pre-clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS01112 ASTN1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Astn1 NCBI NCBI:460