Neurog2 - neurogenin 2 Gene

Also Known as ngn2; Atoh4; ngn-2; Math4A; bHLHa8

Species: Mus musculus

Gene Type: protein coding
Gene ID: 11924

Summary

Enables E-box binding activity. Involved in positive regulation of DNA-binding transcription factor activity. Acts upstream of or within several processes, including nervous system development; positive regulation of neuron differentiation; and positive regulation of transcription by RNA polymerase II. Located in nucleus. Is expressed in several structures, including alimentary system; central nervous system; embryo ectoderm; eye; and integumental system. Orthologous to human NEUROG2 (neurogenin 2). [provided by Alliance of Genome Resources, Apr 2022]

Neurog2 Products (1)

mRNA Protein Name
NM_009718.4 NP_033848.1 neurogenin-2

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables E-box binding IDA
IDA: Inferred from direct assay
14697366 MGI
enables protein binding IPI
IPI: Inferred from physical interaction
15655114 MGI
enables sequence-specific DNA binding IDA
IDA: Inferred from direct assay
17141158 MGI
Biological Process GO Annotation Evidence References Source
acts upstream of Cajal-Retzius cell differentiation IDA
IDA: Inferred from direct assay
18579678 MGI
acts upstream of or within axon guidance IMP
IMP: Inferred from mutant phenotype
12895419 MGI
acts upstream of or within cell fate commitment IGI
IGI: Inferred from genetic interaction
15229646 MGI
acts upstream of or within cell maturation IMP
IMP: Inferred from mutant phenotype
16766700 MGI
acts upstream of or within central nervous system neuron development IGI
IGI: Inferred from genetic interaction
16410412 MGI
acts upstream of or within central nervous system neuron development IMP
IMP: Inferred from mutant phenotype
16410412 MGI
acts upstream of or within dopaminergic neuron differentiation IMP
IMP: Inferred from mutant phenotype
16396906 MGI
acts upstream of or within forebrain development IMP
IMP: Inferred from mutant phenotype
15328020 MGI
acts upstream of or within neurogenesis IDA
IDA: Inferred from direct assay
19050759 MGI
acts upstream of neuron differentiation IDA
IDA: Inferred from direct assay
18579678 MGI
acts upstream of or within neuron migration IMP
IMP: Inferred from mutant phenotype
16396906 MGI
involved in positive regulation of DNA-binding transcription factor activity IDA
IDA: Inferred from direct assay
14697366 MGI
acts upstream of or within positive regulation of neuron differentiation IDA
IDA: Inferred from direct assay
18579678 MGI
acts upstream of or within positive regulation of transcription by RNA polymerase II IDA
IDA: Inferred from direct assay
15655114 MGI
acts upstream of or within positive regulation of transcription by RNA polymerase II IGI
IGI: Inferred from genetic interaction
16648472 MGI
acts upstream of or within positive regulation of transcription by RNA polymerase II IMP
IMP: Inferred from mutant phenotype
16410412 MGI
Cellular Component GO Annotation Evidence References Source
located in nucleus IDA
IDA: Inferred from direct assay
19409883 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

neurogenin-2

  • atonal homolog 4

  • helix-loop-helix protein mATH-4A

  • protein atonal homolog 4

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (2)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS09229 NEUROG2 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-174571 Human NEUROG2 mRNA / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Neurog2 NCBI NCBI:63973