2. Gene
  3. Atp6v1e1 - ATPase, H+ transporting, lysosomal V1 subunit E1 Gene

Atp6v1e1 - ATPase, H+ transporting, lysosomal V1 subunit E1 Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Mus musculus

Also known as p31; Vma4; Atp6e; Atp6e2; Atp6v1e; D6Ertd385e; 2410029D23Rik

Gene ID: 11973 | Gene type: protein coding

About Atp6v1e1

Summary

Enables proton-transporting ATPase activity, rotational mechanism. Acts upstream of or within proton transmembrane transport. Located in several cellular components, including apical plasma membrane; endosome; and microvillus. Is expressed in several structures, including alimentary system; genitourinary system; integumental system; nervous system; and sensory organ. Human ortholog(s) of this gene implicated in autosomal recessive cutis laxa type IIC. Orthologous to human ATP6V1E1 (ATPase H+ transporting V1 subunit E1). [provided by Alliance of Genome Resources, Apr 2022]

Atp6v1e1 Products(1)

mRNA Protein Name
NM_007510.3 NP_031536.2 V-type proton ATPase subunit E 1
Gene Ontology
  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence Reference Source
enables protein binding IPI
IPI: Inferred from physical interaction
23055941 MGI
enables proton-transporting ATPase activity, rotational mechanism IGI
IGI: Inferred from genetic interaction
11872743 MGI
Biological Process GO Annotation Evidence Reference Source
acts upstream of or within proton transmembrane transport IGI
IGI: Inferred from genetic interaction
11872743 MGI
involved in synaptic vesicle lumen acidification EXP
EXP: Inferred from Experiment
28793259 MGI
involved in synaptic vesicle lumen acidification IDA
IDA: Inferred from direct assay
28793259 MGI
involved in synaptic vesicle lumen acidification IMP
IMP: Inferred from mutant phenotype
28793259 MGI
Cellular Component GO Annotation Evidence Reference Source
located in apical plasma membrane IDA
IDA: Inferred from direct assay
11423561 MGI
located in cytoplasm IDA
IDA: Inferred from direct assay
11872743 MGI
located in cytosol IDA
IDA: Inferred from direct assay
16177003 MGI
located in endosome IDA
IDA: Inferred from direct assay
16177003 MGI
located in microvillus IDA
IDA: Inferred from direct assay
18667600 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

V-type proton ATPase subunit E 1

ATPase, H+ transporting, lysosomal 31kDa, V1 subunit E

H(+)-ATPase E-like protein

V-ATPase 31 kDa subunit

V-ATPase subunit E 1

VATPase, H+ transporting, lysosomal V1 subunit E1

vacuolar proton pump subunit E 1

Related Agents

Pre-clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS01229 ATP6V1E1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Atp6v1e1 NCBI NCBI:529