Bnip2 - BCL2/adenovirus E1B interacting protein 2 Gene

Also Known as Nip21; BNIP2beta; 5730523P12Rik

Species: Mus musculus

Gene Type: protein coding
Gene ID: 12175

Summary

Acts upstream of or within several processes, including blastocyst development; centrosome cycle; and positive regulation of intracellular signal transduction. Located in centriole and spindle pole centrosome. Orthologous to human BNIP2 (BCL2 interacting protein 2). [provided by Alliance of Genome Resources, Apr 2022]

Bnip2 Products (3)

mRNA Protein Name
NM_001008238.3 NP_001008239.1 BCL2/adenovirus E1B 19 kDa protein-interacting protein 2 isoform alpha
NM_001374750.1 NP_001361679.1 BCL2/adenovirus E1B 19 kDa protein-interacting protein 2 isoform c
NM_016787.4 NP_058067.2 BCL2/adenovirus E1B 19 kDa protein-interacting protein 2 isoform beta

Gene Ontology

  • Biological Process
  • Cellular Component
Biological Process GO Annotation Evidence References Source
acts upstream of or within blastocyst development IMP
IMP: Inferred from mutant phenotype
19117032 MGI
acts upstream of or within centrosome cycle IMP
IMP: Inferred from mutant phenotype
19117032 MGI
acts upstream of or within positive regulation of MAPK cascade IGI
IGI: Inferred from genetic interaction
20160094 MGI
acts upstream of or within positive regulation of MAPK cascade IMP
IMP: Inferred from mutant phenotype
19244314 MGI
acts upstream of or within positive regulation of neuron differentiation IMP
IMP: Inferred from mutant phenotype
19244314 MGI
acts upstream of or within positive regulation of small GTPase mediated signal transduction IMP
IMP: Inferred from mutant phenotype
19244314 MGI
acts upstream of or within striated muscle cell differentiation IGI
IGI: Inferred from genetic interaction
20160094 MGI
Cellular Component GO Annotation Evidence References Source
located in centriole IDA
IDA: Inferred from direct assay
19117032 MGI
located in spindle pole centrosome IDA
IDA: Inferred from direct assay
19117032 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

BCL2/adenovirus E1B 19 kDa protein-interacting protein 2

  • BCL2/adenovirus E1B 19 kDa-interacting protein 2 beta

  • BCL2/adenovirus E1B 19kDa-interacting protein 1, NIP2

  • BCL2/adenovirus E1B interacting protein 1, NIP2

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS01563 BNIP2 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Bnip2 NCBI NCBI:663