ANKRD9 - ankyrin repeat domain 9 Gene

Species: Homo sapiens

Gene Type: protein coding
Gene ID: 122416

About ANKRD9

Cytogenetic location: 14q32.31 Genomic coordinates (GRCh38): 14:102,501,767-102,509,776 (from NCBI)

This gene has 5 transcripts (splice variants) and 162 orthologues. Broad expression in duodenum (RPKM 15.4), small intestine (RPKM 11.1) and 22 other tissues.

Summary

Enables ubiquitin ligase-substrate adaptor activity. Involved in cellular copper ion homeostasis; proteasome-mediated ubiquitin-dependent protein catabolic process; and protein ubiquitination. Located in cytoplasmic vesicle and cytosol. Part of Cul5-RING ubiquitin Ligase complex. [provided by Alliance of Genome Resources, Apr 2022]

ANKRD9 Products (3)

mRNA Protein Name
NM_001348651.2 NP_001335580.1 ankyrin repeat domain-containing protein 9
NM_001348652.2 NP_001335581.1 ankyrin repeat domain-containing protein 9
NM_152326.4 NP_689539.1 ankyrin repeat domain-containing protein 9

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables ubiquitin-like ligase-substrate adaptor activity IMP
IMP: Inferred from mutant phenotype
30293565 GOA
Biological Process GO Annotation Evidence References Source
involved in intracellular copper ion homeostasis IMP
IMP: Inferred from mutant phenotype
24522796 GOA
involved in proteasome-mediated ubiquitin-dependent protein catabolic process IMP
IMP: Inferred from mutant phenotype
30293565 GOA
involved in protein ubiquitination IMP
IMP: Inferred from mutant phenotype
30293565 GOA
Cellular Component GO Annotation Evidence References Source
part of Cul5-RING ubiquitin ligase complex IDA
IDA: Inferred from direct assay
30293565 GOA
located in cytoplasmic vesicle IDA
IDA: Inferred from direct assay
31337707 GOA
located in cytosol IDA
IDA: Inferred from direct assay
30293565 GOA
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

ANKRD9 Protein Structure

Ank_5

Ank_5: Ankyrin repeats (many copies) (156 - 198)

  • 0
  • 100
  • 200
  • 300
  • 317 a.a.
Protein Preferred Names Protein Names

ankyrin repeat domain-containing protein 9

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS00734 ANKRD9 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Rattus norvegicus ANKRD9 RGD RGD:1307662
Mus musculus ANKRD9 MGD MGI:1921501
Macaca mulatta ANKRD9 VGNC VGNC:84301
Canis familiaris ANKRD9 VGNC VGNC:37915
Bos taurus ANKRD9 VGNC VGNC:25943
Others ANKRD9 NCBI