Hyou1 - hypoxia up-regulated 1 Gene

Also Known as Cab140; Grp170; Orp150; CBP-140

Species: Mus musculus

Gene Type: protein coding
Gene ID: 12282

Summary

Predicted to enable ATP binding activity and ATP hydrolysis activity. Involved in negative regulation of endoplasmic reticulum stress-induced neuron intrinsic apoptotic signaling pathway and response to ischemia. Part of endoplasmic reticulum chaperone complex. Is expressed in embryo and tail. Human ortholog(s) of this gene implicated in immunodeficiency 59. Orthologous to human HYOU1 (hypoxia up-regulated 1). [provided by Alliance of Genome Resources, Apr 2022]

Hyou1 Products (3)

mRNA Protein Name
NM_001411630.1 NP_001398559.1 hypoxia up-regulated protein 1 isoform 2 precursor
NM_001411631.1 NP_001398560.1 hypoxia up-regulated protein 1 isoform 2 precursor
NM_021395.5 NP_067370.3 hypoxia up-regulated protein 1 isoform 1 precursor
Protein Preferred Names Protein Names

hypoxia up-regulated protein 1

  • 140 kDa Ca(2+)-binding protein

  • 150-kDa oxygen regulated protein

  • 170 kDa glucose regulated protein GRP170

  • GRP-170

  • calcium binding protein 140

  • calcium binding protein, 140 kDa

Orthologs Information

Species Symbol Source ID
Homo sapiens Hyou1 NCBI NCBI:10525