2. Gene
  3. Cacna1e - calcium channel, voltage-dependent, R type, alpha 1E subunit Gene

Cacna1e - calcium channel, voltage-dependent, R type, alpha 1E subunit Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Mus musculus

Also known as BII; Cach6; Cav2.3; Cchra1; alpha1E; Cacnl1a6; A430040I15

Gene ID: 12290 | Gene type: protein coding

About Cacna1e

Summary

This gene encodes an integral membrane protein that belongs to the Calcium Channel alpha-1 subunits family. Voltage-sensitive calcium channels mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes. Voltage-dependent calcium channels are multi-subunit complexes, comprised of alpha-1, alpha-2, beta and delta subunits in a 1:1:1:1 ratio. The isoform alpha-1E gives rise to R-type calcium currents and belongs to the high-voltage activated group. Calcium channels containing the alpha-1E subunit may be involved in the modulation of neuronal firing patterns, an important component of information processing. [provided by RefSeq, Jul 2008]

Cacna1e Products(1)

mRNA Protein Name
NM_009782.3 NP_033912.2 voltage-dependent R-type calcium channel subunit alpha-1E
Protein Preferred Names Protein Names

voltage-dependent R-type calcium channel subunit alpha-1E

brain calcium channel II

calcium channel, L type, alpha-1 polypeptide

calcium channel, voltage-dependent, L type, alpha 1E subunit

voltage-gated calcium channel subunit alpha Cav2.3

Related Agents

Pre-clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS01795 CACNA1E Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Cacna1e NCBI NCBI:777