2. Gene
  3. Cacnb1 - calcium channel, voltage-dependent, beta 1 subunit Gene

Cacnb1 - calcium channel, voltage-dependent, beta 1 subunit Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Mus musculus

Also known as CAB1; Cchb1; Cchlb1

Gene ID: 12295 | Gene type: protein coding

About Cacnb1

Summary

Enables high voltage-gated Calcium Channel activity. Acts upstream of or within calcium ion transport and protein targeting to membrane. Located in T-tubule; presynapse; and sarcoplasmic reticulum. Part of voltage-gated Calcium Channel complex. Is expressed in several structures, including diaphragm; lower leg rest of mesenchyme; nervous system; skeletal musculature; and tail paraxial mesenchyme. Orthologous to human CACNB1 (calcium voltage-gated channel auxiliary subunit beta 1). [provided by Alliance of Genome Resources, Apr 2022]

Cacnb1 Products(6)

mRNA Protein Name
NM_001159319.3 NP_001152791.1 voltage-dependent L-type calcium channel subunit beta-1 isoform C
NM_001159320.2 NP_001152792.1 voltage-dependent L-type calcium channel subunit beta-1 isoform D
NM_001282977.2 NP_001269906.1 voltage-dependent L-type calcium channel subunit beta-1 isoform E
NM_001282978.2 NP_001269907.1 voltage-dependent L-type calcium channel subunit beta-1 isoform F
NM_031173.5 NP_112450.1 voltage-dependent L-type calcium channel subunit beta-1 isoform A
NM_145121.4 NP_660099.2 voltage-dependent L-type calcium channel subunit beta-1 isoform B
Gene Ontology
  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence Reference Source
enables high voltage-gated calcium channel activity IGI
IGI: Inferred from genetic interaction
11756409 MGI
enables protein binding IPI
IPI: Inferred from physical interaction
1370480 MGI
enables voltage-gated calcium channel activity IDA
IDA: Inferred from direct assay
1370480 MGI
enables voltage-gated calcium channel activity IMP
IMP: Inferred from mutant phenotype
8943043 MGI
Biological Process GO Annotation Evidence Reference Source
acts upstream of or within calcium ion transport IMP
IMP: Inferred from mutant phenotype
8943043 MGI
acts upstream of or within protein targeting to membrane IMP
IMP: Inferred from mutant phenotype
8943043 MGI
Cellular Component GO Annotation Evidence Reference Source
located in T-tubule IDA
IDA: Inferred from direct assay
8943043 MGI
is active in presynapse IDA
IDA: Inferred from direct assay
19996312 MGI
is active in presynapse IMP
IMP: Inferred from mutant phenotype
19996312 MGI
located in sarcoplasmic reticulum IDA
IDA: Inferred from direct assay
8943043 MGI
part of voltage-gated calcium channel complex IDA
IDA: Inferred from direct assay
10328888 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

voltage-dependent L-type calcium channel subunit beta-1

calcium channel voltage-dependent subunit beta 1

voltage-dependent calcium channel beta1 subunit

Related Agents

Pre-clinical Phase
Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-RS01805 CACNB1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Cacnb1 NCBI NCBI:782