Calb1 - calbindin 1 Gene

Also Known as CB; Calb; Calb-1; Brain-2

Species: Mus musculus

Gene Type: protein coding
Gene ID: 12307

Summary

Enables calcium ion binding activity involved in regulation of postsynaptic cytosolic calcium ion concentration and calcium ion binding activity involved in regulation of presynaptic cytosolic calcium ion concentration. Involved in regulation of long-term synaptic potentiation. Acts upstream of or within several processes, including locomotory behavior; metanephros development; and retina layer formation. Located in several cellular components, including GABA-ergic synapse; hippocampal mossy fiber to CA3 synapse; and neuronal cell body. Is active in glutamatergic synapse. Is expressed in several structures, including alimentary system; genitourinary system; lung; nervous system; and sensory organ. Orthologous to human CALB1 (calbindin 1). [provided by Alliance of Genome Resources, Apr 2022]

Calb1 Products (1)

mRNA Protein Name
NM_009788.4 NP_033918.1 calbindin

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables calcium ion binding involved in regulation of postsynaptic cytosolic calcium ion concentration IDA
IDA: Inferred from direct assay
9037080 MGI
enables calcium ion binding involved in regulation of postsynaptic cytosolic calcium ion concentration IMP
IMP: Inferred from mutant phenotype
9037080 MGI
enables calcium ion binding involved in regulation of presynaptic cytosolic calcium ion concentration IDA
IDA: Inferred from direct assay
12691666 MGI
enables calcium ion binding involved in regulation of presynaptic cytosolic calcium ion concentration IMP
IMP: Inferred from mutant phenotype
12691666 MGI
Biological Process GO Annotation Evidence References Source
acts upstream of or within locomotory behavior IMP
IMP: Inferred from mutant phenotype
12716955 MGI
involved in metanephric collecting duct development IEP
IEP: Inferred from expression pattern
18618131 MGI
involved in metanephric connecting tubule development IEP
IEP: Inferred from expression pattern
18618131 MGI
involved in metanephric distal convoluted tubule development IEP
IEP: Inferred from expression pattern
18618131 MGI
involved in metanephric part of ureteric bud development IEP
IEP: Inferred from expression pattern
18618131 MGI
involved in retina development in camera-type eye IEP
IEP: Inferred from expression pattern
10741426 MGI
involved in retina layer formation IEP
IEP: Inferred from expression pattern
10741426 MGI
Cellular Component GO Annotation Evidence References Source
is active in GABA-ergic synapse IDA
IDA: Inferred from direct assay
12691666 MGI
is active in GABA-ergic synapse IMP
IMP: Inferred from mutant phenotype
12691666 MGI
located in axon IDA
IDA: Inferred from direct assay
11724816 MGI
located in cytoplasm IDA
IDA: Inferred from direct assay
10828532 MGI
located in cytosol IDA
IDA: Inferred from direct assay
15579147 MGI
located in dendrite IDA
IDA: Inferred from direct assay
10973246 MGI
is active in glutamatergic synapse IDA
IDA: Inferred from direct assay
9037080 MGI
is active in glutamatergic synapse IMP
IMP: Inferred from mutant phenotype
9037080 MGI
is active in hippocampal mossy fiber to CA3 synapse IDA
IDA: Inferred from direct assay
12691666 MGI
is active in hippocampal mossy fiber to CA3 synapse IMP
IMP: Inferred from mutant phenotype
12691666 MGI
located in intracellular anatomical structure IDA
IDA: Inferred from direct assay
20040500 MGI
located in neuron projection IDA
IDA: Inferred from direct assay
10989258 MGI
located in neuronal cell body IDA
IDA: Inferred from direct assay
10973246 MGI
located in nucleus IDA
IDA: Inferred from direct assay
10741426 MGI
located in synapse IDA
IDA: Inferred from direct assay
16814779 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

calbindin

  • CalbindinD28K

  • D-28K

  • PCD-29

  • calbindin 1, 28kDa

  • calbindin D28

  • calbindin-28K

  • calbindin-D (28k)

  • spot 35 protein

  • vitamin D-dependent calcium-binding protein, avian-type

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS01826 CALB1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Calb1 NCBI NCBI:793