HYKK - hydroxylysine kinase Gene

Homo sapiens

Also known as AGPHD1

Gene ID: 123688 | Gene type: protein coding

About HYKK

Cytogenetic location: 15q25.1 Genomic coordinates (GRCh38): 15:78,507,577-78,537,373 (from NCBI)

This gene has 6 transcripts (splice variants) and 226 orthologues. Ubiquitous expression in kidney (RPKM 1.5), duodenum (RPKM 1.5) and 24 other tissues.

Summary

Enables hydroxylysine kinase activity. Predicted to be involved in lysine catabolic process. Predicted to be located in mitochondrial matrix. [provided by Alliance of Genome Resources, Apr 2022]

HYKK Products(2)

mRNA	Protein	Name
NM_001013619.4	NP_001013641.2	hydroxylysine kinase isoform 1
NM_001083612.2	NP_001077081.1	hydroxylysine kinase isoform 2

HYKK Protein Structure

APH

0
100
200
300
373 a.a.

Protein Preferred Names

Protein Names

hydroxylysine kinase

5-hydroxy-L-lysine kinase

Related Diseases

Diseases

Alias

Histidinemia

Histidine Ammonia-Lyase Deficiency	Hal Deficiency
Histidase Deficiency	His Deficiency
Histidinuria	Hyperhistidinemia
HISTID	Histidinuria Renal Tubular Defect

Histidine Metabolism Disease

Disturbances Of Histidine Metabolism	Disorder Of Histidine Metabolism
Disturbance Of Histidine Metabolism

Tobacco Addiction

Nicotine Dependence	Tobacco Addiction, Susceptibility To
Nicotine Addiction	Tobacco Use Disorder
Smoking Habit	Nicotine Dependence, Protection Against
Nicotine Addiction, Protection From	Cigarette Habituation
Cigarette Habituation, Susceptibility To	Smoking Habit, Susceptibility To
Nicotine Dependence, Susceptibility To	Nicotine Addiction, Susceptibility To
Addiction, Tobacco, Susceptibility To	Compulsive Tobacco User Syndrome
Tobacco Dependence	Tobacco Dependence Syndrome
Cigarette Addiction	Cigarette Dependence
Smoking Addiction	Smokers Syndrome

Diseases	Alias
Waldenstroem'S Macroglobulinemia	Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma Waldenstroem'S Macroglobulinemia Waldenstroem'S Macroglobulinemia Macroglobulinemia Of Waldenstrom Lymphoplasmacytic Lymphoma With Igm Gammopathy Lymphoplasmacytic Lymphoma

Cat. No.	Product Name	Effect	Purity	Rare Diseases
HY-RS06501	HYKK Human Pre-designed siRNA Set A		/	Unkown

Orthologs Information

Species	Symbol	Source	ID
Macaca mulatta	HYKK	VGNC	VGNC:84349
Mus musculus	HYKK	MGD	MGI:2443139
Rattus norvegicus	HYKK	RGD	RGD:1308677
Bos taurus	HYKK	VGNC	VGNC:30013
Felis catus	HYKK	VGNC	VGNC:104401
Canis familiaris	HYKK	VGNC	VGNC:41845