HYKK - hydroxylysine kinase Gene

Also Known as AGPHD1

Species: Homo sapiens

Gene Type: protein coding
Gene ID: 123688

About HYKK

Cytogenetic location: 15q25.1 Genomic coordinates (GRCh38): 15:78,507,577-78,537,373 (from NCBI)

This gene has 6 transcripts (splice variants) and 226 orthologues. Ubiquitous expression in kidney (RPKM 1.5), duodenum (RPKM 1.5) and 24 other tissues.

Summary

Enables hydroxylysine kinase activity. Predicted to be involved in lysine catabolic process. Predicted to be located in mitochondrial matrix. [provided by Alliance of Genome Resources, Apr 2022]

HYKK Products (2)

mRNA Protein Name
NM_001013619.4 NP_001013641.2 hydroxylysine kinase isoform 1
NM_001083612.2 NP_001077081.1 hydroxylysine kinase isoform 2

Gene Ontology

  • Molecular Function
Molecular Function GO Annotation Evidence References Source
enables hydroxylysine kinase activity IDA
IDA: Inferred from direct assay
22241472 GOA
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

HYKK Protein Structure

APH

APH: Phosphotransferase enzyme family (37 - 285)

  • 0
  • 100
  • 200
  • 300
  • 373 a.a.
Protein Preferred Names Protein Names

hydroxylysine kinase

  • 5-hydroxy-L-lysine kinase

Related Diseases

Diseases Alias
Histidinemia

  • Histidine Ammonia-Lyase Deficiency

  • Hal Deficiency

  • Histidase Deficiency

  • His Deficiency

  • Histidinuria

  • Hyperhistidinemia

  • HISTID

  • Histidinuria Renal Tubular Defect
Histidine Metabolism Disease

  • Disturbances Of Histidine Metabolism

  • Disorder Of Histidine Metabolism

  • Disturbance Of Histidine Metabolism
Tobacco Addiction

  • Nicotine Dependence

  • Tobacco Addiction, Susceptibility To

  • Nicotine Addiction

  • Tobacco Use Disorder

  • Smoking Habit

  • Nicotine Dependence, Protection Against

  • Nicotine Addiction, Protection From

  • Cigarette Habituation

  • Cigarette Habituation, Susceptibility To

  • Smoking Habit, Susceptibility To

  • Nicotine Dependence, Susceptibility To

  • Nicotine Addiction, Susceptibility To

  • Addiction, Tobacco, Susceptibility To

  • Compulsive Tobacco User Syndrome

  • Tobacco Dependence

  • Tobacco Dependence Syndrome

  • Cigarette Addiction

  • Cigarette Dependence

  • Smoking Addiction

  • Smokers Syndrome
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS06501 HYKK Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Macaca mulatta HYKK VGNC VGNC:84349
Mus musculus HYKK MGD MGI:2443139
Rattus norvegicus HYKK RGD RGD:1308677
Bos taurus HYKK VGNC VGNC:30013
Felis catus HYKK VGNC VGNC:104401
Canis familiaris HYKK VGNC VGNC:41845
Others HYKK NCBI