Cbfa2t3 - CBFA2/RUNX1 translocation partner 3 Gene

Also Known as Eto2; ETO-2; MTGR2; Cbfa2t3h; A630044F12Rik

Species: Mus musculus

Gene Type: protein coding
Gene ID: 12398

Summary

Enables chromatin binding activity. Acts upstream of or within negative regulation of transcription by RNA polymerase II. Predicted to be located in nucleoplasm. Predicted to be active in nucleus. Is expressed in several structures, including central nervous system; genitourinary system; mesenchyme derived from splanchnopleure; retina; and spleen. Orthologous to human CBFA2T3 (CBFA2/RUNX1 partner transcriptional co-repressor 3). [provided by Alliance of Genome Resources, Apr 2022]

Cbfa2t3 Products (6)

mRNA Protein Name
NM_001109873.1 NP_001103343.1 protein CBFA2T3 isoform 2
NM_009824.2 NP_033954.2 protein CBFA2T3 isoform 1
NM_177289.1 NP_796263.1 protein CBFA2T3 isoform 3
NM_001109873.1 NP_001103343.1 protein CBFA2T3 isoform 2
NM_009824.2 NP_033954.2 protein CBFA2T3 isoform 1
NM_177289.1 NP_796263.1 protein CBFA2T3 isoform 3

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables chromatin binding IDA
IDA: Inferred from direct assay
19799863 MGI
enables protein binding IPI
IPI: Inferred from physical interaction
16407974 MGI
Biological Process GO Annotation Evidence References Source
acts upstream of or within negative regulation of transcription by RNA polymerase II IGI
IGI: Inferred from genetic interaction
19799863 MGI
Cellular Component GO Annotation Evidence References Source
located in intracellular anatomical structure IDA
IDA: Inferred from direct assay
15231665 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

protein CBFA2T3

  • ETO/MTG8-related protein ETO-2

  • MTG8-related protein 2

  • eight twenty one protein 2

  • myeloid translocation gene-related protein 2

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS01994 CBFA2T3 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Cbfa2t3 NCBI NCBI:863